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Clareo Health | Melanoma Clinical Trials | 3,340 Studies Recruiting

Clinical TrialsMelanoma

Melanoma Clinical Trials

Browse 3,340 clinical trials for melanoma. Find studies that match your criteria and connect with research centers.

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Showing 241-260 of 3,340 trials

CompletedA Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsThis is a first-in-human, open-label, dose escalation study to evaluate the safety and tolerability of pegilodecakin in participants with advanced solid tumors, dosed daily…NCT02009449·Los Angeles, California and 9 others CompletedSurvivorship Promotion In Reducing IGF-1 TrialThis is a prospective, single-center randomized trial with three arms, and an allocation ratio of 1:1:1.NCT02431676·Baltimore, Maryland CompletedTrial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid TumorsThis research trial is testing a combination of two experimental drugs, MSC1936369B (Mitogen-activated protein extracellular signal-regulated kinase (MEK) Inhibitor) and SAR245409…NCT01390818·Scottsdale, Arizona and 7 others

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Data from ClinicalTrials.govTerms

CompletedVaccine Therapy With gp100 and/or Sargramostim in Treating Patients With Malignant MelanomaRATIONALE: Vaccines made from gp100 and sargramostim may make the body build an immune response to kill tumor cells.NCT00003897·Madison, Wisconsin

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

CompletedA Comparison of Nivolumab-based Treatments in a Real-world PD-L1 Positive Metastatic Melanoma Population in the USThe goal of this study is to describe patient characteristics, treatment outcomes and adverse events for patients with metastatic melanoma testing positive for PD-L1 expression…NCT03732560·Parsippany, New Jersey

Not yet recruitingTrial of Temozolomide in BAP1 Mutated Patients With Advanced or Metastatic Cutaneous MelanomaBAP1, or BRCA1-associated protein 1, is a gene involved in DNA repair via homologous recombination and is considered a tumor suppressor gene.NCT07807878

WithdrawnCombination of Anti-CD137 & Ipilimumab in Patients With MelanomaThe purpose of this study is to determine if BMS-663513 administered in combination with ipilimumab to patients with advanced malignant melanoma is safe and tolerableNCT00803374·Los Angeles, California and 6 others

TerminatedA Study of a Monoclonal Antibody, KW-2871, in Patients With Advanced MelanomaThis is a dose escalating cohort study to determine the maximum tolerated dose (MTD) of KW-2871 (in dose cohorts of 60, 80, and 100 mg/m2) when administered with a specified…NCT00199342·Birmingham, Alabama and 1 other

UnknownSYSTEMATIC SYMPTOM ASSESSMENT IN CANCER PATIENTS TREATED WITH IMMUNE CHECKPOINT INHIBITORSImmune-related adverse events (irAEs) can be different in their onset, kinetics and presentation but unlike chemotherapy are seldom predictable.NCT04929353·Perugia, PG

UnknownConcurrent Ipilimumab and Stereotactic Ablative Radiation Therapy (SART) for Oligometastatic But Unresectable MelanomaThe purpose of this study is to evaluate if precisely-targeted radiation therapy, known as stereotactic ablative radiotherapy (SART), given during treatment with the drug…NCT01565837·Las Vegas, Nevada

CompletedTrial of pIL-12/MK-3475 in Metastatic MelanomaThis is a multicenter, Phase II, open-label, 42-patient single-arm trial of intratumoral pIL-12 electroporation (EP) in combination with pembrolizumab in patients with melanoma.NCT02493361·San Francisco, California and 1 other

CompletedPEG-Interferon Alfa-2b and Thalidomide in Treating Patients With Recurrent or Metastatic MelanomaRATIONALE: PEG-interferon alfa-2b may interfere with the growth of tumor cells.NCT00238329·Detroit, Michigan

Active not recruitingA Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid TumorsThe purpose of this study is to test the safety and tolerability of HFB200603 as a single agent and in combination with tislelizumab in patients with advanced cancers.NCT05789069·Los Angeles, California and 10 others

UnknownTo Assess Immunogenicity of Coronavirus Disease 2019 (COVID-19) Vaccine in Cancer Patients Receiving Cancer TreatmentThis is a trial of prospective collection of serial blood samples after administration of COVID-19 vaccine in patients with cancer who are receiving active cancer treatment…NCT04821570·Kansas City, Kansas

CompletedObservational Study for Melanoma Adjuvant Treatment With Tafinlar® + Mekinist® (Dabrafenib + Trametinib)The primary objective for this non-interventional study was to assess the quality of life of melanoma patients under adjuvant treatment with dabrafenib and trametinib in real…NCT04547946·Coimbra, Center and 1 other

CompletedA Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic TumorsThis is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pharmacokinetics of autogene…NCT03289962·Scottsdale, Arizona and 32 others

CompletedUprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV CancerThis phase I/II trial studies the side effects and the best dose of uprosertib when given together with dabrafenib and trametinib and to see how well they work in treating…NCT01902173·Los Angeles, California and 15 others

CompletedBKM120 Combined With Vemurafenib (PLX4032) in BRAFV600E/K Mutant Advanced MelanomaThis is a phase 1/2 clinical trial with the goal of determining whether the addition of the investigational agent BKM120 to vemurafenib will lead to improved 6-month…NCT01512251·San Francisco, California

Not yet recruitingA Study of QL1706 Combined With OH2 Injection in Perioperative Treatment of Stage III Resectable Acral MelanomaThis is a prospective, multicenter, open-label, 1:1 randomized phase II trial enrolling 76 patients with AJCC stage III surgically resectable acral melanoma.NCT07854522

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