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Clareo Health | Melanoma Clinical Trials in Tennessee | 340 Studies

Clinical Trials MelanomaTennessee

Melanoma Clinical Trials in Tennessee

Find 340 clinical trials for melanoma near Tennessee. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 261-280 of 340 trials

Active not recruitingSafety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)This 2-part study will evaluate the safety and efficacy of pembrolizumab (MK-3475) compared to placebo in participants with surgically resected high-risk Stage II melanoma.NCT03553836·Tucson, Arizona and 158 others

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Data from ClinicalTrials.govTerms

CompletedA Study of BIND-014 Given to Patients With Advanced or Metastatic CancerThe goal of this Phase 1 clinical research study is to find the highest safe dose of BIND-014 that can be given in the treatment of patients with advanced or metastatic cancer.NCT01300533·Scottsdale, Arizona and 5 others

TerminatedPembrolizumab With Talimogene Laherparepvec or Placebo in Unresected MelanomaThe primary objectives of the Phase 1b part of the study are to evaluate the safety, as assessed by incidence of dose limiting toxicity (DLT), of talimogene laherparepvec in…NCT02263508·Birmingham, Alabama and 160 others

CompletedStudy of DF6215 in Patients With Advanced Solid TumorsA Phase I/Ib, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 Monotherapy and in…NCT06108479·Los Angeles, California and 20 others

UnknownA Study to Assess PV-10 Chemoablation of Cancer of the LiverThis open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional injection of PV-10 in subjects with…NCT00986661·San Diego, California and 4 others

TerminatedPhase 2 Study of Ipilimumab in Children and Adolescents (12 to < 18 Years) With Previously Treated or Untreated, Unresectable Stage III or Stage lV Malignant MelanomaThe purpose of the study is to comply with the Pediatric Investigation Plan requirements of IpilimumabNCT01696045·Phoenix, Arizona and 31 others

CompletedHigh-Dose Interferon Alfa and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer or MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill kidney cancer or melanoma cells.NCT00003091·Newport Beach, California and 3 others

Active not recruitingIpilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase II trial is studying how well giving ipilimumab with or without sargramostim (GM-CSF) works in treating patients with stage III or stage IV melanoma that…NCT01134614·Birmingham, Alabama and 256 others

CompletedStudy to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the BrainThis is a multi-cohort, open label, Phase II study with Dabrafenib (GSK2118436) and Trametinib (GSK1120212) combination therapy in subject with BRAF mutation-positive melanoma…NCT02039947·Birmingham, Alabama and 46 others

CompletedA Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal MelanomaIMCgp100-102 is a Phase I/II study of the weekly intra-patient escalation dose regimen with IMCgp100 as a single agent in participants with metastatic uveal melanoma (mUM).NCT02570308·La Jolla, California and 25 others

CompletedMAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck CancersThis Phase 1 study is designed as a cell dose escalation trial in HLA-A\*02:01 and HLA-A\*02:06 subjects with MAGE-A10 positive urothelial, melanoma or head and neck tumors.NCT02989064·Boston, Massachusetts and 10 others

CompletedEvaluation of Tumor Response to Ipilimumab in the Treatment of Melanoma With Brain MetastasesTo assess the response of melanoma with brain metastases to ipilimumab treatment while maintaining acceptable tolerability.NCT00623766·Scottsdale, Arizona and 13 others

CompletedTrial of PI-88 With Dacarbazine in Patients With Metastatic MelanomaThe aim of the study is to compare the safety and effectiveness of a new drug called PI-88, when used in combination with an approved chemotherapy drug called dacarbazine, in the…NCT00130442·Tucson, Arizona and 11 others

RecruitingTegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsThis phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or…NCT04851119·Birmingham, Alabama and 20 others

CompletedSargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By SurgeryThis randomized phase III trial studies sargramostim or vaccine therapy alone to see how well they work compared to sargramostim and vaccine therapy together in preventing disease…NCT01989572·Birmingham, Alabama and 147 others

RecruitingStudy to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.This is a Phase 3, multicenter, open-label, randomized, parallel group, treatment study to assess the efficacy and safety of lifileucel in combination with pembrolizumab compared…NCT05727904·Birmingham, Alabama and 81 others

TerminatedTissue Procurement Substudy for Participants in Study CP-MGA271-01The purpose of this study is to gain a better understanding about how the study drug MGA271 works. No test drug will be given in this study.NCT01918930·Los Angeles, California and 6 others

RecruitingA Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid TumorsThis is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1311/BNT324 in subjects with advanced solid tumors.NCT05914116·Tucson, Arizona and 106 others

UnknownSafety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced MalignanciesThe primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies…NCT04137900·Birmingham, Alabama and 23 others

CompletedEfficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in MelanomaThe objective of this study is to evaluate the efficacy and safety of treatment with talimogene laherparepvec compared to subcutaneously administered GM-CSF in patients with…NCT00769704·Tucson, Arizona and 82 others

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