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Clareo Health | Melanoma Clinical Trials in Tennessee | 340 Studies

Clinical Trials MelanomaTennessee

Melanoma Clinical Trials in Tennessee

Find 340 clinical trials for melanoma near Tennessee. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 221-240 of 340 trials

CompletedA Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid TumorsProtocol B8011001 is a Phase 1, open-label, multi-center, multiple-dose, dose escalation and expansion, safety, pharmacokinetics (PK), and pharmacodynamics (PD) study of…NCT02573259·Los Angeles, California and 66 others

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Data from ClinicalTrials.govTerms

TerminatedTrial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant MelanomaThis phase 2 clinical trial randomizes patients with BRAF mutant melanoma to either (1) standard of care (SOC) - BRAF inhibitor vemurafenib in combination with MEK inhibitor…NCT01495988·Los Angeles, California and 13 others

CompletedA Study of DEDN6526A in Patients With Metastatic or Unresectable MelanomaThis multicenter, open-label study will assess the safety and pharmacokinetics of DEDN6526A in patients with metastatic or unresectable melanoma.NCT01522664·Los Angeles, California and 5 others

CompletedCD40 Agonistic Antibody APX005M (Sotigalimab) in Combination With NivolumabThis study is a Phase 1-2 open-label dose escalation study of the immuno-activating monoclonal antibody APX005M administered in combination with nivolumab to adult subjects with…NCT03123783·Tucson, Arizona and 22 others

TerminatedHigh-Dose Aldesleukin and Ipilimumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By SurgeryThis phase II trial studies how well high-dose aldesleukin and ipilimumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery.NCT02203604·Maywood, Illinois and 5 others

TerminatedStudy of IK-595 in RAS- or RAF-altered Advanced TumorsThis is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) effects, and preliminary…NCT06270082·Duarte, California and 14 others

CompletedA Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01949 when given in combination with immune therapies in participants with advanced or…NCT03241173·Birmingham, Alabama and 14 others

UnknownVaccine Therapy for Patients With Stage IV MelanomaThis is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed.NCT00052156·Tucson, Arizona and 76 others

RecruitingA Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor MalignanciesThis is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of…NCT05669430·Los Angeles, California and 12 others

TerminatedA Safety Study of SGN-CD47M in Patients With Solid TumorsThis trial will study SGN-CD47M to find out whether it is an effective treatment for different types of solid tumors and what side effects (unwanted effects) may occur.NCT03957096·Cleveland, Ohio and 4 others

TerminatedA Study to Learn How Safe BAY2666605 is, How it Affects the Body, How it Moves Into, Through and Out of the Body, the Maximum Amount That Can be Given and Its Action Against Tumors in Adult Participants With Skin Cancer That Has Spread to Other Parts of the Body and Other Types of Advanced CancerResearchers are looking for a better way to treat people who have advanced cancer. In this study researchers want to learn more about a new substance called BAY2666605.NCT04809805·Nashville, Tennessee and 2 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

CompletedA Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and LymphomasThis is a phase I study designed to determine the feasibility of transplantation using a novel transplant approach that employs a two-stage haploidentical cell infusion following…NCT01625351·Memphis, Tennessee

Active not recruitingA Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07799933) administered as a single agent and in combination with other…NCT05355701·Fayetteville, Arkansas and 39 others

TerminatedStudy of ADCT-301 in Patients With Selected Advanced Solid TumorsThis study evaluates ADCT-301 in patients with Selected Advanced Solid Tumors.NCT03621982·Palo Alto, California and 8 others

TerminatedIDO Inhibitor Study for Relapsed or Refractory Solid TumorsThis study provides an early evaluation of an entirely new class of small molecule agents directed at disruption or elimination of tumor tolerance, a phenomenon now demonstrated…NCT00739609·Nashville, Tennessee

TerminatedStudy Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600EThis is an open-label, multicenter, single-agent, phase II study of continuous oral Zelboraf (vemurafenib) in participants with locally-advanced, unresectable, stage IIIc or…NCT01586195·Tucson, Arizona and 14 others

Active not recruitingTesting Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has SpreadThis phase II trial compares the effect of dabrafenib and trametinib given continuously to given with a break in treatment (intermittent) in treating patients with stage III-IV…NCT02196181·Birmingham, Alabama and 751 others

RecruitingB7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)3CAR is being done to investigate an immunotherapy for patients with solid tumors.NCT04897321·Memphis, Tennessee

RecruitingStudy of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic CancerThis is a first in human, open-label, multi-center Phase 1 / 2 study to evaluate the safety, tolerability, and initial efficacy of AU-007, also known as imneskibart, in patients…NCT05267626·Miami, Florida and 16 others

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma