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Clareo Health | Melanoma Clinical Trials in Tennessee | 340 Studies

Clinical Trials MelanomaTennessee

Melanoma Clinical Trials in Tennessee

Find 340 clinical trials for melanoma near Tennessee. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Tennessee

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 181-200 of 340 trials

CompletedPF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)This protocol allows patients who completed Coley oncology studies using PF-3512676 (CPG 7909) Injection to continue receiving the treatment until disease progression.NCT00043368·Berkely, California and 31 others TerminatedStudy of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid TumorsONCR-177-101 is a phase 1, open-label, multi-center, dose escalation and expansion study of ONCR-177, an oncolytic Herpes Simplex Virus for intratumoral injection, alone and in…NCT04348916·Duarte, California and 10 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid TumoursThe purpose of this study is to determine the appropriate dosage, safety and effectiveness of the study drug, IPN01194 in adults with advanced solid tumours.NCT06305247·Los Angeles, California and 10 others

TerminatedA Study of Tasisulam-sodium Versus Paclitaxel as Treatment for Metastatic MelanomaThe primary purpose of this study was to see how tasisulam-sodium affected metastatic melanoma when compared against paclitaxel as measured by overall survival.NCT01006252·Birmingham, Alabama and 121 others

TerminatedImmunotherapy Study for Patients With Stage IV MelanomaThe purpose of this study is to examine the effectiveness of immune checkpoint inhibitors (drugs called ipilimumab, nivolumab, or pembrolizumab), either given alone, or in…NCT02054520·Niles, Illinois and 4 others

CompletedA Study of Vemurafenib and GDC-0973 (Cobimetinib) in Participants With BRAFV600E Mutation-Positive Metastatic MelanomaThis open-label, dose-escalation study of vemurafenib in combination with cobimetinib will evaluate the safety, tolerability and pharmacokinetics in participants with BRAFV600…NCT01271803·Los Angeles, California and 9 others

Active not recruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X MutationsTo evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors * To evaluate the safety and tolerability…NCT05907304·San Francisco, California and 28 others

CompletedPhase I/II Study of PDR001 in Patients With Advanced MalignanciesThe purpose of this "first-in-human" study of PDR001 was to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of PDR001…NCT02404441·Baltimore, Maryland and 40 others

CompletedStudy to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant MelanomaIMCgp100 is a new biological therapy designed for the treatment of melanoma skin cancer. The drug is designed to target melanoma cells and stimulate immune cells to kill them.NCT01211262·Los Angeles, California and 8 others

TerminatedGamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV MelanomaThis phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with stage IV melanoma.NCT01120275·Mobile, Alabama and 177 others

TerminatedNivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II ExpressionThis is an open-label, non-randomized two arm Phase 2 study of intravenous nivolumab plus intravenous ipilimumab or intravenous relatlimab in patients with metastatic melanoma…NCT03724968·Nashville, Tennessee

TerminatedA Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid TumorsThis study has 2 phases. The main aims of Phase 1b are: * to check for side effects from modakafusp alfa in adults with locally advanced or metastatic solid tumors.NCT04157517·Duarte, California and 16 others

CompletedStudy to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced CancerThis is a Phase 1, open-label, multi-center, first time in human study of AMP-224 in adult patients with cancer that is not responding to standard therapy.NCT01352884·Detroit, Michigan and 3 others

CompletedStudy of Imprime PGG and Pembrolizumab in Advanced Melanoma and Triple Negative Breast CancerObjective: To determine the Overall Response Rate (ORR) to Imprime PGG + pembrolizumab in subjects with advanced melanoma or metastatic TNBC Safety: To characterize the safety of…NCT02981303·Avondale, Arizona and 9 others

RecruitingA Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid TumorsThis is a proof-of-concept study designed to investigate HER3-DXd monotherapy in locally advanced unresectable or metastatic solid tumors.NCT06172478·Duarte, California and 90 others

TerminatedElesclomol (STA-4783) With Paclitaxel Versus Paclitaxel Alone in Melanoma"Elesclomol (STA-4783), N-malonyl-bis (N'-methyl-N'-thiobenzoylhydrazide) is a new chemical entity with a novel structure. STA-4783 induces an oxidative stress response in cells.NCT00522834·Tucson, Arizona and 100 others

RecruitingPhase 1 Study of PF-08046033 in Advanced Solid TumorsThis is an early-stage (Phase 1) clinical study testing a new study medicine called PF-08046033.NCT07519655·Denver, Colorado and 14 others

CompletedA Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)This is a Phase 1/2, open label study. Phase 1 consists of 2 parts.NCT02327078·Birmingham, Alabama and 23 others

CompletedRegistry Study for Talimogene LaherparepvecA Registry Study to Evaluate the Survival and Long-Term Safety of Subjects Who Previously Received Talimogene Laherparepvec in Amgen or BioVEX-Sponsored Clinical TrialsNCT02173171·Mobile, Alabama and 58 others

Active not recruitingPredicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer TreatmentsThe PROPHETIC study is a prospective, multi-center, international clinical study aimed at developing an algorithm to predict patient outcomes.NCT04056247·Birmingham, Alabama and 40 others

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