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Clareo Health | Melanoma Clinical Trials in Tennessee | 343 Studies

Clinical Trials MelanomaTennessee

Melanoma Clinical Trials in Tennessee

Find 343 clinical trials for melanoma near Tennessee. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Tennessee

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 343 trials

CompletedErlotinib and Bevacizumab in Treating Patients With Stage IV MelanomaRATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00466687·Nashville, Tennessee and 3 others CompletedStudy to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected CancersThe purpose of this study was to assess the safety, tolerability, and efficacy when combining MK-3475 and INCB024360 in participants with certain cancers.NCT02178722·La Jolla, California and 23 others

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Data from ClinicalTrials.govTerms

WithdrawnAutonomic Phenotype Before and After Akt InhibitionSome Akt inhibitors have produced functional cardiovascular effects such as marked hypotension that may limit their clinical benefit.NCT01593579·Nashville, Tennessee

CompletedCollecting Tumor Samples From Patients With Gynecological TumorsThis laboratory study is collecting tumor tissue and blood samples from patients with gynecologic tumors.NCT00897442·Fayetteville, Arkansas and 186 others

CompletedA Study of DF6002 Alone and in Combination With NivolumabThe purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab…NCT04423029·Orange, California and 31 others

CompletedMolecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is MetastaticThis phase II trial studies how well molecularly targeted therapy works in treating patients with melanoma that has spread to other parts of the body.NCT02094872·Scottsdale, Arizona and 7 others

CompletedStudy of DF6215 in Patients With Advanced Solid TumorsA Phase I/Ib, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 Monotherapy and in…NCT06108479·Los Angeles, California and 20 others

Active not recruitingA Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma TreatmentThis study is researching the long-term effects of a combination of experimental drugs called fianlimab and cemiplimab.NCT06848088·Los Angeles, California and 10 others

CompletedPhase I/II Study of PDR001 in Patients With Advanced MalignanciesThe purpose of this "first-in-human" study of PDR001 was to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of PDR001…NCT02404441·Baltimore, Maryland and 40 others

SuspendedA Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid TumorsThis is a first in human, single arm, open label, Phase 1a/1b study to determine the safety, feasibility, and efficacy of a single dose of NeoTCR-P1 T cells in participants with…NCT03970382·Duarte, California and 8 others

Active not recruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X MutationsTo evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors * To evaluate the safety and tolerability…NCT05907304·San Francisco, California and 28 others

TerminatedHigh-Dose Aldesleukin and Ipilimumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By SurgeryThis phase II trial studies how well high-dose aldesleukin and ipilimumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery.NCT02203604·Maywood, Illinois and 5 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

TerminatedTovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid TumorsThis is a Phase 2, multi-center, open-label to evaluate the efficacy and safety of tovorafenib (DAY101) in participants ≥12 years of age with recurrent or progressive melanoma or…NCT04985604·Los Angeles, California and 19 others

CompletedA Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic MelanomaThis open-label single-arm study will evaluate the effect of RO5185426 \[RG7204; PLEXXIKON: PLX4032\] on the pharmacokinetics of five CYP450 substrates (caffeine, warfarin +…NCT01001299·Los Angeles, California and 4 others

RecruitingA Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid TumorsThe purpose of this study is to assess the safety, tolerability, and recommended dose(s) of BMS-986340 as monotherapy and in combination with nivolumab, docetaxel, or Pumitamig in…NCT04895709·Clovis, California and 46 others

CompletedA Study of Vemurafenib Adjuvant Therapy in Participants With Surgically Resected Cutaneous BRAF-Mutant MelanomaThis multicenter, randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of vemurafenib in participants with completely resected, cutaneous BRAF…NCT01667419·Birmingham, Alabama and 206 others

TerminatedA Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With CancerThe purpose of this study is to learn about the safety and effects of the study medicine (called PF-07921585) in people with cancer that has advanced or spread to other parts of…NCT06580938·Fayetteville, Arkansas and 8 others

RecruitingMolecular Analysis of Childhood and Adolescent Melanocytic LesionsThis is an observational, non-therapeutic study to collect clinical and molecular information of pediatric patients with childhood melanocytic lesions.NCT02775643·Memphis, Tennessee

Active not recruitingStudy of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)The Phase 2 study is a multicenter, open-label study of RP1 to further investigate safety and to estimate the efficacy of RP1 at the RP2D in combination with nivolumab in patients…NCT03767348·Birmingham, Alabama and 50 others

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Other Conditions in Tennessee

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma