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Clareo Health | Melanoma Clinical Trials in Philadelphia | 224 Studies

Clinical Trials MelanomaPhiladelphia

Melanoma Clinical Trials in Philadelphia

Find 224 clinical trials for melanoma near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 224 trials

CompletedA Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)The purpose of the study is to assess the efficacy, safety, and tolerability when combining pembrolizumab with epacadostat or placebo in participants with unresectable or…NCT02752074·Birmingham, Alabama and 128 others

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Data from ClinicalTrials.govTerms

Active not recruitingZr89 + PET Companion TrialStudy of Zirconium Zr 89 Crefmirlimab Berdoxa PET/CT as an imaging biomarker for assessing an early response to therapy in patients with advanced melanoma on immunotherapy and…NCT05279027·Philadelphia, Pennsylvania

TerminatedStage IV Surgery Versus Best Medical TherapyThis study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites.NCT01013623·Sacramento, California and 18 others

TerminatedA Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic MelanomaObatoclax Mesylate (GMX1777) is a water-soluble, intravenously-administered pro-drug of GMX1778. GMX1777 is rapidly converted to GMX1778 in vivo.NCT00724841·Philadelphia, Pennsylvania

Active not recruitingA Study of Nivolumab and Hydroxychloroquine or Nivolumab/Ipilimumab and Hydroxychloroquine in Advanced MelanomaThis study will evaluate the safety, tolerability and efficacy (objective response rate) of using hydroxychloroquine (HCQ) in combination with nivolumab and ipilimumab or with…NCT04464759·Philadelphia, Pennsylvania

TerminatedNausea and Vomiting In Patients Receiving Consecutive Days of CisplatinThe purpose of this study is to observe the incidence of nausea with systemic chemotherapy that includes consecutive days (more than one day)of cisplatin medication.NCT00716560·Philadelphia, Pennsylvania

UnknownVaccine Therapy for Patients With Stage IV MelanomaThis is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed.NCT00052156·Tucson, Arizona and 76 others

RecruitingSYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryInternational registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool…NCT03452774·Birmingham, Alabama and 67 others

CompletedIMCgp100 in Advanced Unresectable MelanomaA phase 0, exploratory study of the pharmacodynamics of a single intratumoral dose of IMCgp100, a monoclonal T cell receptor anti-CD3 scFv fusion protein, in subjects with…NCT01209676·Philadelphia, Pennsylvania

CompletedColony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003597·Long Beach, California and 23 others

CompletedA Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)This study is being conducted to determine if a combination of AZD6244 given orally twice a day with standard doses of selected chemotherapies will be safe and tolerable for…NCT00600496·Detroit, Michigan and 3 others

Active not recruitingIpilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic MelanomaThe main purpose of this study is to determine the safety of combining ipilimumab and nivolumab with hypofractionated radiotherapy to a single tumor in patients with metastatic…NCT03646617·Lancaster, Pennsylvania and 2 others

CompletedA Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive MelanomasThis is a first-in-human, multi-center clinical study to determine the safety, Maximum Tolerated Dose (MTD) and/or Optimal Biological Dose (OBD) as well as the optimal schedule…NCT04551352·Boston, Massachusetts and 13 others

CompletedImaging FDG Flare in MelanomaUp to 35 adult patients with metastatic melanoma planning to start pembrolizumab will be enrolled in this study with a target enrollment of 30 evaluable subjects.NCT02791594·Philadelphia, Pennsylvania

CompletedDigital vs. Printed Photographs: Impact on Skin Self-ExaminationsThe primary aim is to determine the impact of using digital photographs on a mobile device versus printed photographs on skin self-examination rates.NCT02520622·Philadelphia, Pennsylvania

TerminatedITIL-168 in Advanced MelanomaDELTA-1 is a phase 2 clinical trial to evaluate the efficacy and safety of ITIL-168 in adult subjects with advanced melanoma who have previously been treated with a PD-1 inhibitor.NCT05050006·La Jolla, California and 21 others

CompletedIntrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural EffusionsRATIONALE: Using BG00001 to insert the gene for interferon-beta into a person's pleural cavity may improve the body's ability to fight cancer.NCT00066404·Philadelphia, Pennsylvania

TerminatedCMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced MelanomaCMP-001-011 is a Phase 2/3 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) compared to nivolumab monotherapy administered to participants with unresectable or…NCT04695977·Phoenix, Arizona and 19 others

CompletedA Study of SEA-CD40 Given With Other Drugs in CancersThis trial is being done to see if an experimental drug (SEA-CD40) works when it's given with other cancer drugs to treat some types of cancer.NCT04993677·Springdale, Arkansas and 28 others

TerminatedA Phase 1 Study of [225Ac]-FPI-1434 InjectionThis is a first-in-human Phase 1/2, non-randomized, multi-centre, open-label clinical study designed to investigate safety, tolerability, PK, and preliminary anti-tumour activity…NCT03746431·Duarte, California and 12 others

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