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Clareo Health | Melanoma Clinical Trials in Philadelphia | 224 Studies

Clinical Trials MelanomaPhiladelphia

Melanoma Clinical Trials in Philadelphia

Find 224 clinical trials for melanoma near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 224 trials

CompletedA Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)The goal of this clinical trial is to test the safety and efficacy of KVA12123 alone or combined with pembrolizumab in patients with advanced solid tumors.NCT05708950·Santa Monica, California and 6 others CompletedAn Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have SpreadThe purpose of the study is to determine safety and effectiveness of experimental medication BMS-986205 when combined with Nivolumab and in combination with both Nivolumab and…NCT02658890·Tucson, Arizona and 46 others

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Data from ClinicalTrials.govTerms

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

RecruitingBiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot StudyThis phase II trial studies the good and bad effects of the combination of drugs called cabozantinib and nivolumab in treating patients with melanoma or squamous cell head and…NCT05136196·Phoenix, Arizona and 228 others

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

Active not recruitingGEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid TumorsThe goal of this trial is to learn about the antibody GEN1042 when it is used alone and when it is used together with another antibody cancer drug, pembrolizumab (with or without…NCT04083599·Anchorage, Alaska and 75 others

TerminatedPhase I Safety and Dosimetry Study in Patients With Confirmed Metastatic MelanomaThis is an open-label, single dose study for patients 18 years of age or older with confirmed metastatic melanoma.NCT00747825·Philadelphia, Pennsylvania

Active not recruitingA Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable MelanomaThe purpose of this study is to demonstrate that the study drug exposure level of the nivolumab + relatlimab FDC subcutaneous (SC) formulation is not worse than nivolumab +…NCT05625399·Phoenix, Arizona and 148 others

RecruitingA Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)This study is researching an experimental drug called fianlimab (also known as REGN3767), combined with another medication called cemiplimab (also known as REGN2810), called…NCT06246916·Chandler, Arizona and 111 others

CompletedA Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant MelanomaThe main purpose of this research study is to compare the safety, tolerability, and anti tumor activity of an investigational drug, ABI-007 versus Dacarbazine in patients with…NCT00864253·Birmingham, Alabama and 111 others

CompletedA Study of GSK2118436 in BRAF Mutant Metastatic MelanomaBRF113710 is a Phase II, single-arm, open-label study to assess the efficacy, safety, and tolerability of GSK2118436 administered twice daily as a single agent in subjects with…NCT01153763·Los Angeles, California and 22 others

RecruitingNeoadjuvant Darovasertib in Primary Uveal MelanomaThis is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)NCT07015190·Scottsdale, Arizona and 93 others

WithdrawnA CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and NivolumabThe main purpose of this study is to investigate the utility of the new investigational imaging agent ⁸⁹Zr Df-IAB22M2C (CD8 PET/CT tracer) to monitor CD8 T-cell expansion and…NCT04955262·Duarte, California and 2 others

CompletedA Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid TumorsPhase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in…NCT05864144·Los Angeles, California and 9 others

CompletedS0008: Chemotherapy Plus Biological Therapy in Treating Patients With MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells.NCT00006237·Birmingham, Alabama and 296 others

CompletedStudy of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV MelanomaThe primary goal of this study is to determine if people with metastatic melanoma who receive Heat Shock Protein-Peptide Complex - 96 (HSPPC-96 or Oncophage) after surgery live…NCT00039000·Birmingham, Alabama and 76 others

CompletedMulti-center Phase I/IIa Trial of an Autologous Tumor Lysate (TL) + Yeast Cell Wall Particles (YCWP) + Dendritic Cells (DC) Vaccine in Addition to Standard of Care Checkpoint Inhibitor of Choice in Metastatic Melanoma Patients With Measurable Disease.Assess the safety and tumor response of utilizing an autologous tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine given in combination with standard of care (SoC)…NCT02678741·Birmingham, Alabama and 6 others

TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

CompletedStudy in Patients With Unresectable And Metastatic Melanoma: The Optimize StudyThis study evaluates the different patterns of care for patients who have unresectable or metastatic melanoma.NCT02780089·Muscle Shoals, Alabama and 65 others

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