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Clareo Health | Melanoma Clinical Trials in Philadelphia | 224 Studies

Clinical Trials MelanomaPhiladelphia

Melanoma Clinical Trials in Philadelphia

Find 224 clinical trials for melanoma near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 21-40 of 224 trials

Active not recruitingA Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)The purpose of this study is to learn if intismeran autogene which is an individualized neoantigen therapy (INT; formerly, called messenger ribonucleic acid \[mRNA\]-4157) with…NCT05933577·Springdale, Arkansas and 164 others

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Data from ClinicalTrials.govTerms

CompletedCirculating Tumor Material in Colorectal Cancer and MelanomaObservational study to allow the collection of blood and medical information to evaluate the role of circulating tumor material in patients with colorectal cancer and melanomaNCT02907086·Philadelphia, Pennsylvania

TerminatedTesting Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node InvolvementThis phase II trial studies how well encorafenib and binimetinib work before surgery in treating patients with BRAF V600-mutated stage IIIB-D melanoma that has spread to the lymph…NCT04221438·Los Angeles, California and 9 others

Active not recruitingTesting Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the BrainThis phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer…NCT06500455·Tucson, Arizona and 269 others

TerminatedVaccine Therapy Compared With Interferon Alfa in Treating Patients With Stage III MelanomaRATIONALE: Vaccines made from a person's melanoma cells may make the body build an immune response to kill tumor cells.NCT00003715·Rancho Mirage, California and 16 others

CompletedStudy of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic MelanomaProspective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin 2 (IL-2) after a…NCT02360579·La Jolla, California and 56 others

CompletedCollecting Tumor Samples From Patients With Gynecological TumorsThis laboratory study is collecting tumor tissue and blood samples from patients with gynecologic tumors.NCT00897442·Fayetteville, Arkansas and 186 others

CompletedA Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid TumorsPhase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in…NCT05864144·Los Angeles, California and 9 others

CompletedImaging FDG Flare in MelanomaUp to 35 adult patients with metastatic melanoma planning to start pembrolizumab will be enrolled in this study with a target enrollment of 30 evaluable subjects.NCT02791594·Philadelphia, Pennsylvania

CompletedA Study of GSK2118436 in BRAF Mutant Metastatic MelanomaBRF113710 is a Phase II, single-arm, open-label study to assess the efficacy, safety, and tolerability of GSK2118436 administered twice daily as a single agent in subjects with…NCT01153763·Los Angeles, California and 22 others

CompletedVaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines made from peptides may make the body build an immune response to kill tumor cells.NCT00071981·Palo Alto, California and 64 others

CompletedPhase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck CancerTo determine a safe and effective doses of two biologic drugs, erlotinib and bevacizumab when used with chemotherapy and radiation therapy in advanced head and neck cancerNCT00405405·Philadelphia, Pennsylvania

RecruitingMelanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous MelanomaPatients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin.NCT03860883·Mobile, Alabama and 191 others

CompletedIpilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well ipilimumab with or without high-dose recombinant interferon alpha-2b works in treating patients with stage III-IV melanoma that…NCT01708941·Birmingham, Alabama and 275 others

TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

CompletedMDX-010 Antibody, MDX-1379 Melanoma Vaccine, or MDX-010/MDX-1379 Combination Treatment for Patients With Unresectable or Metastatic MelanomaThe purpose of this study is to determine the safety and efficacy of MDX-010 (ipilimumab, BMS-734016) (anti-CTLA4) in combination with MDX-1379 (gp100, BMS-734019) in patients…NCT00094653·Tucson, Arizona and 208 others

CompletedTrial of Autologous, Hapten-Modified Vaccine in Patients With Stage III or IV MelanomaThe purpose of this study is to determine whether a vaccine composed of patients' own melanoma cells treated with the chemical, dinitrophenyl (DNP)(called a hapten), is safe and…NCT00257465·Tucson, Arizona and 6 others

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

TerminatedStudy CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)This study is an open-label Phase 1/2 evaluation of CB-839 in combination with nivolumab in participants with clear cell renal cell carcinoma, melanoma, and non-small cell lung…NCT02771626·Scottsdale, Arizona and 16 others

CompletedA Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsThis research study is done to test how well different types of cancer respond to the drug called larotrectinib.NCT02576431·Palo Alto, California and 97 others

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma