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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 457 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 457 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 121-140 of 457 trials

CompletedRelationship Between Tumor Mutation Burden and Predicted Neo-antigen Burden in Patients With Advanced Melanoma or Bladder Cancer Treated With Nivolumab or Nivolumab Plus Ipilimumab (CA209-260)The purpose of this study is to investigate the characteristics of tumors in patients treated with nivolumab and to identify features that help to predict a good or bad response…NCT02553642·Farmington, Connecticut and 4 others CompletedBiological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other TumorsRATIONALE: Biological therapies such as hu14.18-interleukin-2 fusion protein use different ways to stimulate the immune system and stop cancer cells from growing.NCT00003750·Little Rock, Arkansas and 58 others

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Data from ClinicalTrials.govTerms

CompletedA Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and…NCT03517488·Los Angeles, California and 16 others

CompletedMulticentre, Dose Finding, Ph II,CP-4055 in Comb. With Sorafenib - Patients With Metastatic Malignant MelanomaPatients with metastatic malignant melanoma will receive CP-4055 200 mg/m2/day intravenously (IV) on Day 1-5 every four weeks and sorafenib 400 mg b.i.d. (twice daily) every day…NCT00498836·Pittsburgh, Pennsylvania and 5 others

TerminatedStudy of Temzolomide and Gleevec in Advanced MelanomaThis study has been designed to evaluate the side effects of Gleevec when given in combination with Temzolomide; and to learn more about how these drugs work in the body and…NCT00667953·Philadelphia, Pennsylvania

CompletedSafety Study of Recombinant Vaccinia Virus to Treat Refractory Solid TumorsThis is a Phase I, open-label, dose-escalation trial in patients with advanced/metastatic solid tumors refractory to standard therapy; tumors may include malignant melanoma…NCT00625456·Billings, Montana and 3 others

CompletedA Study of SEA-CD40 Given With Other Drugs in CancersThis trial is being done to see if an experimental drug (SEA-CD40) works when it's given with other cancer drugs to treat some types of cancer.NCT04993677·Springdale, Arkansas and 28 others

RecruitingMelanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous MelanomaPatients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin.NCT03860883·Mobile, Alabama and 191 others

CompletedPhotodynamic Therapy in Treating Patients With Stage III or Stage IV MelanomaRATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. Photodynamic therapy may be effective in treating melanoma.NCT00007969·Denver, Colorado and 5 others

Active not recruitingA Study of Nivolumab and Hydroxychloroquine or Nivolumab/Ipilimumab and Hydroxychloroquine in Advanced MelanomaThis study will evaluate the safety, tolerability and efficacy (objective response rate) of using hydroxychloroquine (HCQ) in combination with nivolumab and ipilimumab or with…NCT04464759·Philadelphia, Pennsylvania

RecruitingA Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung CancerThis is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung…NCT05361174·Los Angeles, California and 10 others

TerminatedTrial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis FungoidesThis is a multicenter, open-label, phase 1 study conducted to test intratumoral injections of TTI-621 in subjects that have relapsed and refractory percutaneously accessible solid…NCT02890368·Duarte, California and 6 others

Active not recruitingTacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic CancersThis phase I trial studies how well tacrolimus, nivolumab, and ipilimumab work in treating kidney transplant recipients with cancer that cannot be removed by surgery…NCT03816332·Tampa, Florida and 6 others

Active not recruitingNeoadjuvant PD-1 Blockade in Patients with Stage IIB/C MelanomaThe main purpose of this study is to determine the rate of positive sentinel lymph nodes (i.e. the closest draining lymph node(s) to the primary melanoma site) and to test whether…NCT03757689·Louisville, Kentucky and 2 others

CompletedVaccine Therapy in Treating Patients With Stage III or Stage IV MelanomaRATIONALE: Vaccines made from a person's dendritic cells mixed with tumor peptides and proteins may help the body build an effective immune response to kill tumor cells.NCT00390338·Pittsburgh, Pennsylvania and 1 other

CompletedUsing an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2The goal of this clinical trial is to explore feasibility, acceptability, and effectiveness of end-of-life conversation game "Hello" as a tool to help individuals with various…NCT06384417·Hershey, Pennsylvania

CompletedA Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced MelanomaThis is a Phase III, double-blinded, placebo-controlled, randomized, multicenter study designed to evaluate the efficacy, safety, and pharmacokinetics of atezolizumab +…NCT02908672·Birmingham, Alabama and 109 others

WithdrawnA CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and NivolumabThe main purpose of this study is to investigate the utility of the new investigational imaging agent ⁸⁹Zr Df-IAB22M2C (CD8 PET/CT tracer) to monitor CD8 T-cell expansion and…NCT04955262·Duarte, California and 2 others

CompletedA Study to Compare Nivolumab Drug Product Process D to Nivolumab Drug Product Process C in Participants With Stage IIIa/b/c/d or Stage IV Melanoma After Complete ResectionThe purpose of this study is to compare the drug levels, immunogenicity and safety of Nivolumab Process D to Nivolumab Process C after complete resection of stage IIIa/b/c/d or…NCT03980314·Hartford, Connecticut and 36 others

RecruitingStudy of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in MelanomaPhase I, open label, dose-escalation, and safety study designed to assess the safety and biologic activity of the investigational agent CBL0137 in combination with standard of…NCT05498792·Philadelphia, Pennsylvania

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Other Conditions in Pennsylvania

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