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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 457 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 457 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 281-300 of 457 trials

RecruitingA Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or…NCT06022029·Los Angeles, California and 15 others Active not recruitingAdjuvant Treatment Determined By Pathological Response To Neoadjvuant NivolumabSubjects with resectable melanoma will receive neoadjuvant nivolumab followed by surgical resection.NCT04013854·Durham, North Carolina and 2 others RecruitingEvolution of Metabolic and Immune Dysfunction in In-transit MelanomaMelanoma in-transit metastases (ITMs) continue to represent a therapeutic dilemma, in that no standard method of treatment has been uniformly adopted.NCT04658303·Pittsburgh, Pennsylvania

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Data from ClinicalTrials.govTerms

TerminatedTrial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant MelanomaThis phase 2 clinical trial randomizes patients with BRAF mutant melanoma to either (1) standard of care (SOC) - BRAF inhibitor vemurafenib in combination with MEK inhibitor…NCT01495988·Los Angeles, California and 13 others

RecruitingA Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory MelanomaThe goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma.NCT06624644·Newport Beach, California and 8 others

TerminatedTesting Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node InvolvementThis phase II trial studies how well encorafenib and binimetinib work before surgery in treating patients with BRAF V600-mutated stage IIIB-D melanoma that has spread to the lymph…NCT04221438·Los Angeles, California and 9 others

CompletedImmunogenicity and Biomarker Analysis of Neoadjuvant Ipilimumab for MelanomaIpilimumab is a manufactured monoclonal antibody, much like the antibodies usually made by the human body to fight off infection; however it is not known why the human body does…NCT00972933·Pittsburgh, Pennsylvania

CompletedLC Bead Embolization Agent With Doxorubicin in the Treatment Liver Metastasis From MelanomaThe purpose of this study is to determine if LC beads loaded with Doxorubicin are a safe and effective treatment for melanoma that has spread to the liver.NCT01010984·Louisville, Kentucky and 2 others

CompletedCD40 Agonistic Antibody APX005M (Sotigalimab) in Combination With NivolumabThis study is a Phase 1-2 open-label dose escalation study of the immuno-activating monoclonal antibody APX005M administered in combination with nivolumab to adult subjects with…NCT03123783·Tucson, Arizona and 22 others

TerminatedStudy of CDX-3379, a Human Monoclonal Antibody Targeting ERBB3, in Combination With the MEK Inhibitor, Trametinib, in Patients With Advanced Stage NRAS Mutant and BRAF/NRAS Wildtype (WT) MelanomaThe main goal of this study is to test if it is safe and effective to give CDX-3379 together to treat advanced melanoma in patients with the NRAS mutation and BRAF/NRAS wildtype.NCT03580382·New York, New York and 1 other

TerminatedStudy of IK-595 in RAS- or RAF-altered Advanced TumorsThis is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) effects, and preliminary…NCT06270082·Duarte, California and 14 others

CompletedA Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01949 when given in combination with immune therapies in participants with advanced or…NCT03241173·Birmingham, Alabama and 14 others

CompletedA Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant MelanomaThe main purpose of this research study is to compare the safety, tolerability, and anti tumor activity of an investigational drug, ABI-007 versus Dacarbazine in patients with…NCT00864253·Birmingham, Alabama and 111 others

UnknownVaccine Therapy for Patients With Stage IV MelanomaThis is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed.NCT00052156·Tucson, Arizona and 76 others

CompletedA Study of Intratumoral IMO-2125 in Patients With Refractory Solid TumorsThis is a Phase 1b study that incorporates dose expansion cohorts to further evaluate promising clinical or biological activity.NCT03052205·Scottsdale, Arizona and 11 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

CompletedPhase 1 Study of GRN-1201 in HLA-A*02 Subjects With Resected MelanomaThis is a study of an investigational cancer vaccine called GRN-1201. Treatment with the GRN-1201 vaccine is a type of immunotherapy.NCT02696356·Cincinnati, Ohio and 3 others

CompletedA Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced MelanomaThe objective of this study is to evaluate the clinical activity of the GSK2132231A immunotherapeutic in patients with MAGE-A3 positive unresectable metastatic melanoma presenting…NCT00942162·Los Angeles, California and 62 others

TerminatedStage IV Surgery Versus Best Medical TherapyThis study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites.NCT01013623·Sacramento, California and 18 others

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

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Other Conditions in Pennsylvania

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma