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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 460 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 460 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 281-300 of 460 trials

TerminatedQUILT-2.008: Study of ALT-801 With Cisplatin in Patients With Metastatic MelanomaThis is a Phase Ib/II, open-label, multi-center, competitive enrollment and dose-escalation study of ALT-801 combined with cisplatin.NCT01029873·Los Angeles, California and 7 others CompletedMulti-center Phase I/IIa Trial of an Autologous Tumor Lysate (TL) + Yeast Cell Wall Particles (YCWP) + Dendritic Cells (DC) Vaccine in Addition to Standard of Care Checkpoint Inhibitor of Choice in Metastatic Melanoma Patients With Measurable Disease.Assess the safety and tumor response of utilizing an autologous tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine given in combination with standard of care (SoC)…NCT02678741·Birmingham, Alabama and 6 others CompletedStudy of Imprime PGG and Pembrolizumab in Advanced Melanoma and Triple Negative Breast CancerObjective: To determine the Overall Response Rate (ORR) to Imprime PGG + pembrolizumab in subjects with advanced melanoma or metastatic TNBC Safety: To characterize the safety of…NCT02981303·Avondale, Arizona and 9 others

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Data from ClinicalTrials.govTerms

Active not recruitingIpilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies ipilimumab to see how well it works compared to high-dose interferon alfa-2b in treating patients with high-risk stage III-IV melanoma that…NCT01274338·Birmingham, Alabama and 936 others

RecruitingA Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid TumorsThis is a two-part Phase 1, open label, multi-center, single arm, non-randomized, multiple dose, safety, pharmacokinetic (PK) and preliminary efficacy study of single agent…NCT06326411·San Francisco, California and 22 others

CompletedEPO906 Therapy in Patients With Advanced MelanomaThis study will examine whether the new investigational drug EPO906, given by intravenous infusion (IV directly into the vein), is effective in shrinking tumors and preventing the…NCT00035165·Aurora, Colorado and 5 others

RecruitingEvolution of Metabolic and Immune Dysfunction in In-transit MelanomaMelanoma in-transit metastases (ITMs) continue to represent a therapeutic dilemma, in that no standard method of treatment has been uniformly adopted.NCT04658303·Pittsburgh, Pennsylvania

TerminatedLive Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid TumorsThis is an open label, safety and preliminary efficacy study of MRx0518 in combination with pembrolizumab in patients with solid tumours (non small cell lung cancer, renal cell…NCT03637803·Kansas City, Kansas and 4 others

TerminatedStudy of IK-595 in RAS- or RAF-altered Advanced TumorsThis is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) effects, and preliminary…NCT06270082·Duarte, California and 14 others

CompletedCP-675,206 In Patients With Advanced MelanomaThe purpose of this study is to assess the efficacy, safety, and tolerability of monoclonal antibody therapy using 2 regimens for the treatment of advanced melanomaNCT00086489·Los Angeles, California and 8 others

CompletedVolociximab in Combination With DTIC in Patients With Metastatic Melanoma Not Previously Treated With ChemotherapyThis clinical trial is being conducted to determine tumor response and preliminary safety of a monoclonal antibody that specifically binds to a cell surface receptor (α5β1…NCT00099970·Birmingham, Alabama and 6 others

CompletedStudy to Compare the Efficacy and Safety of Two CC-5013 Dose Regimens in Subjects With Metastatic Malignant MelanomaSubjects are randomized to one of two treatment arms. All subjects are screened for eligibility within 28 days prior to randomization.NCT00055562·Tucson, Arizona and 30 others

RecruitingInvestigating Real-Time Immunotherapy Symptoms StudyThe goal of this study is to evaluate the feasibility of using information from wearable devices and self-reported symptoms to remotely monitor patients during immunotherapy.NCT07280715·Pittsburgh, Pennsylvania

CompletedA Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic MelanomaThe purpose of the study is to test the effectiveness (how well the drug works), safety, and tolerability of the investigational drug called NKTR-214, when combined with nivolumab…NCT03635983·Tucson, Arizona and 166 others

RecruitingA Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or…NCT06022029·Los Angeles, California and 15 others

TerminatedUse of Fiber-optic Probe for Non-invasive Diagnosis of Melanoma and Assessment of Impact of Ultraviolet (UV) Exposure on SkinThis study is designed to collect information about melanoma using a research probe, a device placed only on the skin.NCT01085396·Pittsburgh, Pennsylvania and 2 others

CompletedTrial of Lymphoseek in Intraoperative Localization of Lymph Nodes in Breast Cancer and MelanomaData from this pivotal clinical trial will be used to support a marketing application (i.e., NDA) for Navidea's Lymphoseek for use in intraoperative localization of lymph tissue…NCT00671918·Alexander City, Alabama and 14 others

CompletedRADVAX™: A STRATIFIED PHASE I/II DOSE ESCALATION TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOLLOWED BY IPILIMUMAB IN METASTATIC MELANOMAThe primary objective is to determine the maximum tolerated hypofractionated radiotherapy dose (MTD) to a solitary metastatic focus ('index lesion') when followed by ipilimumab…NCT01497808·Philadelphia, Pennsylvania

CompletedInterpolated Flap StudyThe primary purpose of this study is to address the limited knowledge regarding patient well- being and nasal function after interpolated flap repair of post-Mohs surgical defects…NCT04164550·Philadelphia, Pennsylvania

Active not recruitingZimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory MelanomaThe main goal of this study is to establish the proportion of patients with objective response to zimberelimab/domvanalimab in PD-1 R/R melanoma patients.NCT05130177·Pittsburgh, Pennsylvania

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Other Conditions in Pennsylvania

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma