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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 457 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 457 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 241-260 of 457 trials

TerminatedA Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid TumorsThis study has 2 phases. The main aims of Phase 1b are: * to check for side effects from modakafusp alfa in adults with locally advanced or metastatic solid tumors.NCT04157517·Duarte, California and 16 others Not yet recruitingPICSTAT Pilot Study for CD8 PET/CT-Guided Lifileucel Treatment in Advanced MelanomaThis prospective, single-center pilot study is being performed to find out whether Zr-89 crefmirlimab berdoxam "CD8 PET/CT" scans can improve the effectiveness of the…NCT07700121·Philadelphia, Pennsylvania

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Data from ClinicalTrials.govTerms

No longer availableExpanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to LiverThe safety and efficacy of CS-PHP-melphalan has been evaluated in a phase 3 trial conducted in the same patient population as well as using the same melphalan dosing as proposed…NCT01728051·Santa Monica, California and 5 others

CompletedDendritic Cell Vaccination in Patients With Advanced MelanomaThe purpose of this study is to investigate a method of using dendritic cells (a kind of white blood cell) as a vaccine to stimulate your own immune system to react to your…NCT03092453·Philadelphia, Pennsylvania

CompletedStudy of Nivolumab (BMS-936558) Plus Ipilimumab Compared With Ipilimumab Alone in the Treatment of Previously Untreated, Unresectable, or Metastatic MelanomaThe primary purpose of this study is to compare the objective response rate, as determined by investigators, of Nivolumab combined with Ipilimumab versus Ipilimumab monotherapy in…NCT01927419·San Francisco, California and 20 others

CompletedHepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to MelanomaRATIONALE: Drugs used in chemotherapy, such as melphalan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.NCT00324727·Santa Monica, California and 11 others

TerminatedHD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic MelanomaThis is a research study to evaluate treatment of metastatic melanoma patients with a combination of drugs.NCT01683188·Tucson, Arizona and 20 others

CompletedStudy of Imprime PGG and Pembrolizumab in Advanced Melanoma and Triple Negative Breast CancerObjective: To determine the Overall Response Rate (ORR) to Imprime PGG + pembrolizumab in subjects with advanced melanoma or metastatic TNBC Safety: To characterize the safety of…NCT02981303·Avondale, Arizona and 9 others

CompletedStudy of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial LesionsThe purpose of this study is to determine whether HF10 is safe and effective in the treatment of head and neck cancer or solid tumors with cutaneous and/or superficial lesions.NCT01017185·The Bronx, New York and 4 others

CompletedTemsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid TumorsThis phase I trial is studying the side effects and best dose of temsirolimus when given together with bryostatin 1 in treating patients with unresectable or metastatic solid…NCT00112476·Philadelphia, Pennsylvania

CompletedMultiple Antigen-Engineered DC Vaccine for MelanomaThis clinical trial is to determine if the addition of a standard of care drug, interferon-alfa 2b (IFN), with an investigation vaccine will have any affect on the immune system…NCT01622933·Pittsburgh, Pennsylvania

TerminatedElesclomol (STA-4783) With Paclitaxel Versus Paclitaxel Alone in Melanoma"Elesclomol (STA-4783), N-malonyl-bis (N'-methyl-N'-thiobenzoylhydrazide) is a new chemical entity with a novel structure. STA-4783 induces an oxidative stress response in cells.NCT00522834·Tucson, Arizona and 100 others

TerminatedA Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsThis study will evaluate the efficacy and safety of alectinib in participants with Anaplastic Lymphoma Kinase (ALK)-positive locally advanced or metastatic solid tumors other than…NCT04644315·Culver City, California and 28 others

CompletedA Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)This is a Phase 1/2, open label study. Phase 1 consists of 2 parts.NCT02327078·Birmingham, Alabama and 23 others

CompletedImaging FDG Flare in MelanomaUp to 35 adult patients with metastatic melanoma planning to start pembrolizumab will be enrolled in this study with a target enrollment of 30 evaluable subjects.NCT02791594·Philadelphia, Pennsylvania

CompletedSafety and Efficacy Study of Vemurafenib and High-dose Interferon Alfa-2b in MelanomaThis is a dose-seeking and efficacy study of combined BRAF Inhibitor Vemurafenib and High-dose Interferon alfa-2b for therapy of advanced melanoma.NCT01943422·Pittsburgh, Pennsylvania

CompletedSafety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic MelanomaThe purpose of this research study is to see if the study drug, CT-011, is safe to give and if it helps people with melanoma that has spread to other areas of their body.NCT01435369·New Haven, Connecticut and 17 others

Active not recruitingA Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid TumorsThe purpose of this study is to test the safety and tolerability of HFB200603 as a single agent and in combination with tislelizumab in patients with advanced cancers.NCT05789069·Los Angeles, California and 10 others

CompletedDose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant MelanomaThe purpose of this study is to determine the safety and tolerability of treatment with BMS-936558 (MDX-1106) in combination with Ipilimumab (BMS-734016) when given at the same…NCT01024231·New Haven, Connecticut and 3 others

RecruitingTebentafusp-tebn With LDT in Metastatic UMThis study is a multicenter, open label phase I/ II trial to assess the safety and clinical efficacy of tebentafusp-tebn in combination with liver-directed therapies in…NCT06626516·Philadelphia, Pennsylvania

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