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Clareo Health | Melanoma Clinical Trials in Michigan | 270 Studies

Clinical Trials MelanomaMichigan

Melanoma Clinical Trials in Michigan

Find 270 clinical trials for melanoma near Michigan. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Michigan

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 270 trials

TerminatedMEK Inhibitor PD-325901 To Treat Advanced Breast Cancer, Colon Cancer, And Melanoma.MEK is a critical member of the MAPK pathway involved in growth and survival of cancer cells. PD-325901 is a new drug designed to block this pathway and kill cancer cells.NCT00147550·Birmingham, Alabama and 16 others TerminatedStudy of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid TumorsA prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL \[LN-144/LN-145 (lifileucel)\] in combination…NCT03645928·La Jolla, California and 33 others

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Data from ClinicalTrials.govTerms

Active not recruitingTH1902 in Patients With Advanced Solid TumorsOpen label first-in-human study of TH1902 in solid cancer, with 4 sequential parts: Part 1 (dose escalation): patients with recurrent advanced solid tumors (all comers) that have…NCT04706962·Detroit, Michigan and 5 others

CompletedS0508: Thalidomide and Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By SurgeryRATIONALE: Thalidomide may stop the growth of melanoma by blocking blood flow to the tumor.NCT00104988·Anchorage, Alaska and 131 others

CompletedCobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or After Treatment With Previous Immunotherapy and Atezolizumab Monotherapy in Participants With Previously Untreated Advanced MelanomaThis study will evaluate the preliminary efficacy, safety, and pharmacokinetics of cobimetinib and atezolizumab in participants with advanced BRAF V600-wild type (WT), metastatic…NCT03178851·Scottsdale, Arizona and 42 others

TerminatedTesting Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node InvolvementThis phase II trial studies how well encorafenib and binimetinib work before surgery in treating patients with BRAF V600-mutated stage IIIB-D melanoma that has spread to the lymph…NCT04221438·Los Angeles, California and 9 others

CompletedA Study of DEDN6526A in Patients With Metastatic or Unresectable MelanomaThis multicenter, open-label study will assess the safety and pharmacokinetics of DEDN6526A in patients with metastatic or unresectable melanoma.NCT01522664·Los Angeles, California and 5 others

RecruitingA Study of MGC026 in Participants With Advanced Solid TumorsThe study is designed to understand the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary antitumor activity of MGC026 in participants with relapsed or…NCT06242470·Los Angeles, California and 11 others

TerminatedStudy of IK-595 in RAS- or RAF-altered Advanced TumorsThis is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) effects, and preliminary…NCT06270082·Duarte, California and 14 others

CompletedA Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01949 when given in combination with immune therapies in participants with advanced or…NCT03241173·Birmingham, Alabama and 14 others

Active not recruitingBasket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor an NTRK1/2/3, ROS1, or ALK…NCT02568267·Phoenix, Arizona and 119 others

CompletedA Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant MelanomaThe main purpose of this research study is to compare the safety, tolerability, and anti tumor activity of an investigational drug, ABI-007 versus Dacarbazine in patients with…NCT00864253·Birmingham, Alabama and 111 others

CompletedA Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid TumorsIn this four-part study, NKTR-214 was administered in combination with nivolumab and with/without other anticancer therapies.NCT02983045·La Jolla, California and 57 others

UnknownVaccine Therapy for Patients With Stage IV MelanomaThis is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed.NCT00052156·Tucson, Arizona and 76 others

RecruitingA Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor MalignanciesThis is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of…NCT05669430·Los Angeles, California and 12 others

CompletedA Study of MDX-1106 in Patients With Selected Refractory or Relapsed MalignanciesTo evaluate the safety, tolerability, efficacy, and pharmacokinetics of MDX-1106 when administered to patients with advanced non-small cell lung cancer, colorectal cancer…NCT00441337·Baltimore, Maryland and 3 others

CompletedA Study of the Effects of ALKS 4230 (Nemvaleukin Alfa) on Subjects With Solid TumorsTo better understand the safety and tolerability of ALKS 4230 in humansNCT02799095·Denver, Colorado and 30 others

CompletedA Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced MelanomaThe objective of this study is to evaluate the clinical activity of the GSK2132231A immunotherapeutic in patients with MAGE-A3 positive unresectable metastatic melanoma presenting…NCT00942162·Los Angeles, California and 62 others

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

CompletedDasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryRATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00700882·Little Rock, Arkansas and 152 others

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