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Clareo Health | Melanoma Clinical Trials in Massachusetts | 361 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 361 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 61-80 of 361 trials

RecruitingThe Cancer of the Pancreas Screening-5 CAPS5)StudyJohns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins.NCT02000089·New Haven, Connecticut and 8 others TerminatedA Phase Ib Study of LXH254-centric Combinations in NSCLC or MelanomaTo characterize safety and tolerability and identify a recommended dose and regimen for the LXH254 in combination with LTT462 or trametinib or ribociclib.NCT02974725·San Diego, California and 31 others

Melanoma Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedSRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (DRAGON)This was a multi-center, open-label, Phase 1, first-in-human (FIH), dose-escalation, and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK)…NCT04291079·Fullerton, California and 21 others

CompletedPH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced MelanomaThe purpose of this study is to evaluate pharmacodynamic changes of Nivolumab and Nivolumab in combination with Ipilimumab treatment on the biomarkers measured in the peripheral…NCT01621490·Los Angeles, California and 13 others

RecruitingStereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain MetastasesThe purpose of this study is to determine whether AGuIX (Activation and Guidance of Irradiation by X-ray) gadolinium-based nanoparticles make radiation work more effectively in…NCT04899908·Boston, Massachusetts and 1 other

TerminatedA Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced MelanomaThe primary purpose of this study is to demonstrate that the NEO-PV-01 vaccine, either with APX005M or ipilimumab, and nivolumab is safe for the treatment of patients with…NCT03597282·Scottsdale, Arizona and 7 others

Active not recruitingA Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic MelanomaThe purpose of this study is to learn about the effects of three study medicines (encorafenib, binimetinib, and pembrolizumab) given together for the treatment of melanoma…NCT04657991·Orlando, Florida and 150 others

Active not recruitingDabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 MelanomaThis phase III trial studies how well initial treatment with ipilimumab and nivolumab followed by dabrafenib and trametinib works and compares it to initial treatment with…NCT02224781·Birmingham, Alabama and 837 others

CompletedA Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsThis is a first-in-human, open-label, dose escalation study to evaluate the safety and tolerability of pegilodecakin in participants with advanced solid tumors, dosed daily…NCT02009449·Los Angeles, California and 9 others

TerminatedA Phase 1b Trial of ATRC-101 in Adults With Advanced Solid MalignanciesATRC-101-A01 is a Phase 1b, open-label dose escalation and expansion trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a…NCT04244552·Phoenix, Arizona and 18 others

CompletedNilotinib in TKI Resistant or Intolerant Patients With Metastatic Mucosal, Acral, or Chronically Sun Damaged MelanomaGiven the poor prognosis and limited treatment options available for patients with mucosal or acral/lentiginous melanomas who develop metastatic disease, genetic discoveries of…NCT00788775·Santa Monica, California and 7 others

Active not recruitingIDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal MelanomaThis is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be…NCT05987332·Scottsdale, Arizona and 67 others

CompletedGSK3359609 Plus Tremelimumab for the Treatment of Advanced Solid TumorsThe purpose of this study is to evaluate if the combination of GSK3359609 and tremelimumab is safe and tolerable (Part 1) and provides significant survival benefit to subjects…NCT03693612·Boston, Massachusetts and 7 others

TerminatedRO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast CancerThis randomized phase I/II trial studies the side effects and the best dose of RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) when given together with…NCT01217411·Boston, Massachusetts and 1 other

TerminatedMSB0010445 and Stereotactic Body Radiation Therapy in Advanced MelanomaThis is a Phase 2a, open-label, parallel group, partly randomized dose escalation trial to assess the safety and efficacy of a low dose, an intermediate dose, and high dose…NCT01973608·Rockland, Massachusetts

Active not recruitingTesting the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant MelanomaThis phase I/II trial studies the side effects and best dose of dabrafenib, trametinib, and navitoclax and to see how well they work in treating patients with BRAF mutant melanoma…NCT01989585·Phoenix, Arizona and 48 others

CompletedOptical Frequency Domain Imaging for Non-melanoma Skin CancersThe purpose of this research study is to find out if a non-invasive imaging device called Optical Frequency Domain Imaging (OFDI) can help doctors to see the tissue and blood…NCT01662713·Boston, Massachusetts

CompletedA Study of LGK974 in Patients With Malignancies Dependent on Wnt LigandsThe primary purpose of this study was to find the recommended dose of LGK974 as a single agent and in combination with PDR001 that can be safely given to adult patients with…NCT01351103·Los Angeles, California and 19 others

TerminatedTroriluzole or Placebo Plus Ipi Plus Nivo in Mel Brain MetsThe purpose of this research is to test the safety and effectiveness of the investigational combination of Troriluzole, ipilimumab, and nivolumab, and to learn whether this…NCT04899921·Boston, Massachusetts and 1 other

Active not recruitingA Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced MelanomaThis phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients…NCT02339571·Birmingham, Alabama and 762 others

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