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Clareo Health | Melanoma Clinical Trials in Houston | 428 Studies

Clinical Trials MelanomaHouston

Melanoma Clinical Trials in Houston

Find 428 clinical trials for melanoma near Houston, Texas. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 428 trials

RecruitingA Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid TumorsThis is a proof-of-concept study designed to investigate HER3-DXd monotherapy in locally advanced unresectable or metastatic solid tumors.NCT06172478·Duarte, California and 93 others

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Data from ClinicalTrials.govTerms

CompletedSafety and Efficacy of LAG525 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.This study was to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and anti-tumor activity of LAG525 as a single agent and in combination with…NCT02460224·New York, New York and 23 others

Active not recruitingPhase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic MelanomaThe goal of this clinical research study is to find the recommended dose of OBX-115 in combination with acetazolamide that can be given to patients with metastatic melanoma…NCT05470283·Houston, Texas

CompletedSubstudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)Substudy 02A is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study.NCT04305041·Los Angeles, California and 35 others

CompletedA Study of LGK974 in Patients With Malignancies Dependent on Wnt LigandsThe primary purpose of this study was to find the recommended dose of LGK974 as a single agent and in combination with PDR001 that can be safely given to adult patients with…NCT01351103·Los Angeles, California and 19 others

CompletedA Study of Vemurafenib in Previously Treated Patients With Metastatic MelanomaThis open-label single arm study will assess the efficacy, safety and tolerability of Vemurafenib in previously treated patients with metastatic melanoma.NCT00949702·Los Angeles, California and 14 others

CompletedA Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic MelanomaThis is an open-label, multicenter, Phase Ib, dose-escalation and cohort-expansion study of atezolizumab (anti-programmed death-ligand 1 \[PD-L1\] antibody) in combination with…NCT01656642·Los Angeles, California and 7 others

CompletedPhase II Trial of Allovectin-7® for Metastatic MelanomaThe purpose of this clinical trial is to determine if Allovectin-7®, an experimental gene-based immunotherapy, can shrink melanoma tumors.NCT00044356·Tucson, Arizona and 15 others

TerminatedA Phase I Study of TPI 287 - Temozolomide Combination in MelanomaThe goal of the Phase I portion of this study is to find the highest tolerable dose of TPI 287 that can be given in combination with Temodar (temozolomide) to patients with…NCT01067066·Houston, Texas

RecruitingMolecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy ProgramThis study performs standardized testing of tumor tissue samples to learn which genes are mutated (have changed) in order to provide personalized cancer therapy options to cancer…NCT01772771·Houston, Texas

RecruitingA Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)This study is researching an experimental drug called fianlimab (also known as REGN3767), combined with another medication called cemiplimab (also known as REGN2810), called…NCT06246916·Chandler, Arizona and 111 others

RecruitingMelanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous MelanomaPatients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin.NCT03860883·Mobile, Alabama and 191 others

CompletedA Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 MelanomaTo compare the safety and efficacy of Allovectin-7® versus Dacarbazine (DTIC)or Temozolomide (TMZ) in subjects with recurrent stage 3 or stage 4 melanoma.NCT00395070·Tucson, Arizona and 87 others

TerminatedStudy CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)This study is an open-label Phase 1/2 evaluation of CB-839 in combination with nivolumab in participants with clear cell renal cell carcinoma, melanoma, and non-small cell lung…NCT02771626·Scottsdale, Arizona and 16 others

RecruitingA Study of VET3-TGI in Patients With Solid TumorsVET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers.NCT06444815·Los Angeles, California and 6 others

UnknownStudy of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesStudy of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesNCT04913337·Los Angeles, California and 26 others

TerminatedPhase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced MalignanciesThis phase Ib trial studies the side effects and best dose of selinexor when given together with several different standard chemotherapy or immunotherapy regimens in treating…NCT02419495·Conroe, Texas and 4 others

CompletedGene Therapy and Ganciclovir in Treating Patients With Stage IV MelanomaRATIONALE: Inserting a modified herpesvirus gene into a person's melanoma cells may make the cancer more sensitive to the antiviral agent ganciclovir.NCT00005057·Bethesda, Maryland and 2 others

TerminatedIPI Biochemotherapy for Chemonaive Patients With Metastatic MelanomaThe goal of the Phase I part of this clinical research study is to find the highest tolerable dose of the drug Yervoy (ipilimumab) that can be given with the drugs Temodar…NCT01409174·Houston, Texas

TerminatedRO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast CancerThis randomized phase I/II trial studies the side effects and the best dose of RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) when given together with…NCT01217411·Boston, Massachusetts and 1 other

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