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Clareo Health | Melanoma Clinical Trials in Houston | 428 Studies

Clinical Trials MelanomaHouston

Melanoma Clinical Trials in Houston

Find 428 clinical trials for melanoma near Houston, Texas. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 428 trials

CompletedA Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic CancerThe purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other…NCT02857270·Washington D.C., District of Columbia and 12 others TerminatedStudy to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for RecurrenceThe main purpose of this study is to compare the efficacy of bempegaldesleukin plus nivolumab versus nivolumab in patients with completely resected Stage IIIA/B/C/D, or Stage IV…NCT04410445·Scottsdale, Arizona and 211 others

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Data from ClinicalTrials.govTerms

CompletedA Study of ASN007 in Patients With Advanced Solid TumorsThe study is divided into two parts. The first part of the study will test various doses of ASN007 to find out the highest safe dose to test in five specific groups.NCT03415126·Tampa, Florida and 4 others

CompletedVaccine Therapy With or Without Cyclophosphamide in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV MelanomaRATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells.NCT00118274·Philadelphia, Pennsylvania and 2 others

CompletedFT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid TumorsFT500 is an off-the-shelf, iPSC-derived NK cell product that can bridge innate and adaptive immunity, and has the potential to overcome multiple mechanisms of immune checkpoint…NCT03841110·San Diego, California and 3 others

TerminatedPF-06952229 Treatment in Adult Patients With Advanced Solid TumorsA Phase 1 dose escalation and expansion study evaluating safety, tolerability and pharmacokinetics of PF-06952229 in adult patients with advanced solid tumors.NCT03685591·Scottsdale, Arizona and 14 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

Active not recruitingA Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid TumorsThis study aims to assess the safety, tolerability, pharmacokinetics, and preliminary efficacy of APG-115, an MDM2 inhibitor, either alone or in combination with pembrolizumab, a…NCT03611868·Tucson, Arizona and 20 others

CompletedStudy to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the BrainThis is a multi-cohort, open label, Phase II study with Dabrafenib (GSK2118436) and Trametinib (GSK1120212) combination therapy in subject with BRAF mutation-positive melanoma…NCT02039947·Birmingham, Alabama and 46 others

RecruitingIntratumoral N17350 in Advanced Solid TumorsThe goal of this clinical trial is to learn if N17350 works to treat advanced solid tumors in adults.NCT07339176·Los Angeles, California and 8 others

CompletedPembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic MelanomaThis randomized phase II trial studies how well giving pembrolizumab with standard chemotherapy, tumor infiltrating lymphocytes (TIL), and aldesleukin works in treating patients…NCT02500576·Houston, Texas

WithdrawnNeoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma ParticipantsThe purpose of this study is to evaluate the role of neoadjuvant immunotherapy and to demonstrate high pathologic complete response (pCR) and near pCR rates in melanoma…NCT04495010·Gilbert, Arizona and 117 others

CompletedLow Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the BrainThis phase II trial studies the side effects and how well low dose ipilimumab works in combination with pembrolizumab in treating patients with melanoma that has spread to the…NCT03873818·Houston, Texas

CompletedDovitinib for Patients With Tumor Pathway Activations Inhibited by DovitinibThe purpose of this signal seeking study was to determine whether treatment with dovitinib (TKI258) demonstrated sufficient efficacy in select pathway-activated solid tumors…NCT01831726·Birmingham, Alabama and 48 others

CompletedPhase II Study of Tesetaxel in Metastatic MelanomaThe goal of this clinical research study is to learn if tesetaxel can help to control metastatic melanoma. The safety of this drug will also be studied.NCT01064713·Houston, Texas

Active not recruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)Stage 1: To select the optimal dose of naporafenib + trametinib to be studied in Stage 2.NCT06346067·Phoenix, Arizona and 58 others

RecruitingA Beta-only IL-2 ImmunoTherapY StudyThis is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor…NCT05086692·San Diego, California and 26 others

Active not recruitingBevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain MetastasesThis phase II trial studies how well bevacizumab and atezolizumab with or without cobimetinib work in treating patients with untreated melanoma that has spread to the brain (brain…NCT03175432·Houston, Texas

Active not recruitingIDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal MelanomaThis is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be…NCT05987332·Scottsdale, Arizona and 67 others

RecruitingA Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid TumorsThe purpose of this study is to assess the safety, tolerability, and recommended dose(s) of BMS-986340 as monotherapy and in combination with nivolumab, docetaxel, or Pumitamig in…NCT04895709·Clovis, California and 46 others

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