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Clareo Health | Melanoma Clinical Trials in Florida | 494 Studies

Clinical Trials MelanomaFlorida

Melanoma Clinical Trials in Florida

Find 494 clinical trials for melanoma near Florida. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Florida

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 401-420 of 494 trials

RecruitingA Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid TumorsThis is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1311/BNT324 in subjects with advanced solid tumors.NCT05914116·Tucson, Arizona and 106 others

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Data from ClinicalTrials.govTerms

UnknownSafety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced MalignanciesThe primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies…NCT04137900·Birmingham, Alabama and 23 others

CompletedEfficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in MelanomaThe objective of this study is to evaluate the efficacy and safety of treatment with talimogene laherparepvec compared to subcutaneously administered GM-CSF in patients with…NCT00769704·Tucson, Arizona and 82 others

CompletedA Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function MutationsThis study employs a 2-stage design that aims to evaluate the efficacy and safety of ENV- 101, a potent Hedgehog (Hh) pathway inhibitor, in patients with refractory advanced solid…NCT05199584·Los Angeles, California and 15 others

TerminatedModified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV MelanomaThis phase I trial studies the side effects and best dose of a modified virus called VSV-IFNbetaTYRP1 in treating patients with stage III-IV melanoma.NCT03865212·Jacksonville, Florida and 1 other

CompletedPattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology PracticeThis is an observational, multicenter study in participants treated with nivolumab for the approved indications of melanoma and Lung cancer in Australia, the EU, Switzerland, the…NCT02847728·Palm Springs, California and 93 others

RecruitingSafety and Efficacy of OBX-115 in Advanced Solid TumorsThis is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.NCT06060613·Los Angeles, California and 9 others

Active not recruitingA Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced MelanomaThe purpose of this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab monotherapy in treating unresectable melanoma or…NCT03470922·Tucson, Arizona and 126 others

CompletedDabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD).This was a two-arm, randomized, double-blind Phase III study of dabrafenib in combination with trametinib versus 2 placebos in the adjuvant treatment of melanoma after surgical…NCT01682083·Birmingham, Alabama and 167 others

TerminatedTovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid TumorsThis is a subprotocol of Master Protocol DAY101-102 and is a Phase 1b/2, multi-center, open label subprotocol of participants ≥12 years of age, with recurrent or progressive solid…NCT07121829·Los Angeles, California and 9 others

RecruitingA Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain MetastasesThis phase II trial compares the effect of encorafenib, binimetinib, and nivolumab versus ipilimumab and nivolumab in treating patients with BRAF- V600 mutant melanoma that has…NCT04511013·Birmingham, Alabama and 330 others

CompletedStudy of Aerosolized Sargramostim in Treating Patients With Melanoma Metastatic to the LungRATIONALE: Colony-stimulating factors, such as sargramostim, may help the body's immune system to kill cancer cells.NCT00005610·Scottsdale, Arizona and 17 others

SuspendedDNX-2440 for Resectable Colorectal Liver MetastasisThe purpose of this study is to test an experimental oncolytic adenovirus called DNX-2440 in patients with resectable multifocal (≥ 2 lesions) liver metastasis, who are scheduled…NCT04714983·Tampa, Florida

Active not recruitingIpilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies ipilimumab to see how well it works compared to high-dose interferon alfa-2b in treating patients with high-risk stage III-IV melanoma that…NCT01274338·Birmingham, Alabama and 936 others

CompletedProof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory MelanomaThe purpose of this first in human study is to evaluate the feasibility, safety, and efficacy of administering TBio-4101 (tumor infiltrating lymphocytes \[TIL\]) after receiving a…NCT05628883·Tampa, Florida

UnknownVaccine Therapy in Treating Patients With Malignant MelanomaRATIONALE: Vaccines made from tumor cells may help the body build an effective immune response to kill tumor cells.NCT00128583·Palm Springs, California and 10 others

TerminatedCMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced MelanomaCMP-001-011 is a Phase 2/3 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) compared to nivolumab monotherapy administered to participants with unresectable or…NCT04695977·Phoenix, Arizona and 19 others

TerminatedA Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.The purpose of this study is to learn about the: * safety (the effect of the study medicine on the participant's body), * effects of the study medicine alone or in combination…NCT06546553·Beverly Hills, California and 7 others

TerminatedA Study of Adjuvant Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab for Resected High-Risk Melanoma in Participants With High-Risk Stage II-IV Melanoma (MK-7684A-010/KEYVIBE-010)The primary purpose of this study is to compare pembrolizumab/vibostolimab to pembrolizumab with respect to recurrence-free survival (RFS).NCT05665595·La Jolla, California and 204 others

CompletedRAD001 Plus Bevacizumab in Metastatic MelanomaThis is a non-randomized, open label Phase II study comparing bevacizumab and everolimus in the treatment of metastatic melanoma.NCT00591734·Fort Myers, Florida and 14 others

Other Conditions in Florida

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma