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Clareo Health | Melanoma Clinical Trials in Florida | 494 Studies

Clinical Trials MelanomaFlorida

Melanoma Clinical Trials in Florida

Find 494 clinical trials for melanoma near Florida. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Florida

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 361-380 of 494 trials

CompletedNAUTILUS: OKI-179 Plus Binimetinib in Patients with Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)The NAUTILUS study is a Phase 1b/2, multi-center, open-label study in which patients with activating mutations in the RAS pathway (Phase 1b) and patients with NRAS-mutated…NCT05340621·Phoenix, Arizona and 11 others CompletedCP-675,206 Versus Either Dacarbazine Or Temozolomide In Patients Without Prior TherapyThis is a Phase 3, multi-national, open-label, 2-arm randomized study in patients with surgically incurable metastatic melanoma who have received no prior chemotherapy, or…NCT00257205·Huntsville, Alabama and 142 others

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Data from ClinicalTrials.govTerms

CompletedA Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)This study will evaluate the efficacy, safety, and pharmacokinetics of treatment combinations in cancer immunotherapy (CIT)-naive participants with resectable Stage III melanoma…NCT05116202·Duarte, California and 13 others

CompletedPhase 3 Study of Nivolumab or Nivolumab Plus Ipilimumab Versus Ipilimumab Alone in Previously Untreated Advanced Melanoma (CheckMate 067)The purpose of this study is to show that Nivolumab and/or Nivolumab in combination with Ipilimumab will extend progression free survival and overall survival compared to…NCT01844505·Gilbert, Arizona and 149 others

TerminatedA Pilot Study of Pivanex in Patients With Malignant MelanomaThis pilot study will assess the safety and efficacy of Pivanex alone in patients with malignant melanoma who have relapsed after treatment with chemotherapy or Interleukin-2…NCT00087477·Miami Beach, Florida

CompletedCombining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic MelanomaThe purpose of this Pilot Study is to investigate the safety, side effects, and benefits of tumor- infiltrating lymphocytes (TILs) when they are given with the drug nivolumab.NCT02652455·Tampa, Florida

CompletedA Study to Investigate the Novel Agent BNT111 and Cemiplimab in Combination or as Single Agents in Patients With Advanced Melanoma That Has Not Responded to Other Forms of TreatmentThis is an open-label, randomized, multi-site, Phase II, interventional trial designed to evaluate the efficacy, tolerability, and safety of BNT111 + cemiplimab in anti-programmed…NCT04526899·Tucson, Arizona and 48 others

TerminatedA Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)This is a Phase 1b/2 dose-optimization study to evaluate safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of avelumab (MSB0010718C) in combination…NCT02554812·Encinitas, California and 87 others

CompletedA Study of Tasisulam in Treating Participants With Malignant MelanomaThe primary purpose of this study is to determine the objective response rate (complete and partial response) for participants who receive tasisulam after one prior systemic…NCT00383292·Los Angeles, California and 12 others

Active not recruitingObservational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)The primary objective of this study is to develop and train the Elephas live tumor diagnostic platform and determine the ex-vivo accuracy of the Elephas Score using in-vivo RECIST…NCT05520099·Little Rock, Arkansas and 11 others

Active not recruitingA Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid TumorsTScan Therapeutics is developing cellular therapies across multiple solid tumors in which autologous participant-derived engeneered T cells are engineered to express a T cell…NCT05973487·Scottsdale, Arizona and 20 others

CompletedStudy Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive MelanomaTwo-arm, randomized, prospective, open-label, multi-center, phase III study to compare the efficacy and safety of MEK162 (45 mg BID) versus dacarbazine (1000 mg/m2 IV every 3…NCT01763164·Fayetteville, Arkansas and 228 others

UnknownInterleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Stage IV Melanoma Metastatic to the LiverRATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill tumor cells.NCT00039234·Santa Monica, California and 18 others

CompletedStudy in Patients With Unresectable And Metastatic Melanoma: The Optimize StudyThis study evaluates the different patterns of care for patients who have unresectable or metastatic melanoma.NCT02780089·Muscle Shoals, Alabama and 65 others

AvailableExpanded Access Program of AMTAGVI That is Out of Specification for Commercial ReleaseThe objective of this expanded access protocol is to provide access to Out Of Specification (OOS) AMTAGVI treatment to patients.NCT05398640·Gilbert, Arizona and 47 others

RecruitingA Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsThis is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with…NCT05592626·Sacramento, California and 18 others

Active not recruitingSafety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)This 2-part study will evaluate the safety and efficacy of pembrolizumab (MK-3475) compared to placebo in participants with surgically resected high-risk Stage II melanoma.NCT03553836·Tucson, Arizona and 158 others

CompletedA Study of BIND-014 Given to Patients With Advanced or Metastatic CancerThe goal of this Phase 1 clinical research study is to find the highest safe dose of BIND-014 that can be given in the treatment of patients with advanced or metastatic cancer.NCT01300533·Scottsdale, Arizona and 5 others

RecruitingNodal Radiation Therapy for Sentinel Lymph Node Positive MelanomaThis phase II trial seeks to determine the role of nodal radiation therapy after sentinel lymph node biopsy (SLNB) for patients with high risk sentinel lymph node positive…NCT04594187·Jacksonville, Florida and 2 others

Active not recruitingStudy of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult ParticipantsThis study is planned to test the safety and tolerability of the TIL regimen. The study will also test how well TIL fights cancer.NCT06566092·Aurora, Colorado and 4 others

Other Conditions in Florida

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma