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Clareo Health | Melanoma Clinical Trials in California | 691 Studies

Clinical Trials MelanomaCalifornia

Melanoma Clinical Trials in California

Find 691 clinical trials for melanoma near California. Connect with research centers in your area.

All Melanoma trials nationwide All trials in California

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 561-580 of 691 trials

RecruitingA Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal MelanomaThe purpose of this study is to measure the clinical benefits of the combination of RP2 and nivolumab as compared with the combination of nivolumab and ipilimumab in patients with…NCT06581406·Scottsdale, Arizona and 32 others

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Data from ClinicalTrials.govTerms

TerminatedA Study of Tasisulam-sodium Versus Paclitaxel as Treatment for Metastatic MelanomaThe primary purpose of this study was to see how tasisulam-sodium affected metastatic melanoma when compared against paclitaxel as measured by overall survival.NCT01006252·Birmingham, Alabama and 121 others

TerminatedA Study of Epacadostat and Nivolumab in Combination With Immune Therapies in Participants With Advanced or Metastatic Malignancies (ECHO-208)The purpose of this study is to determine the safety, tolerability, and efficacy of epacadostat when given in combination with nivolumab and ipilimumab, and in combination with…NCT03347123·Birmingham, Alabama and 4 others

CompletedIntratumoral PH-762 for Cutaneous CarcinomaThe goal of this clinical trial is to evaluate the safety and tolerability of intratumoral injections of PH-762 in squamous cell carcinoma, melanoma, or Merkel cell carcinomas of…NCT06014086·Gilbert, Arizona and 4 others

CompletedStudy of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic MelanomaThe primary purpose of this study is to evaluate the efficacy of novel spartalizumab (PDR001) combinations in previously treated unresectable or metastatic melanomaNCT03484923·Los Angeles, California and 29 others

RecruitingSafety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain MetastasisThis multi-site, Phase 1/2 clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen of NEO212 alone for the…NCT06047379·Beverly Hills, California and 7 others

Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

RecruitingA Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NRAS-mutated advanced or…NCT04913285·Los Angeles, California and 47 others

Active not recruitingTipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment TrialThis phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have recurred or spread to other places in the body (advanced)…NCT04284774·Birmingham, Alabama and 171 others

Active not recruitingTesting Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the BrainThis phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer…NCT06500455·Tucson, Arizona and 269 others

CompletedAn Investigational Immuno-therapy Study of Nivolumab Combined With Ipilimumab Compared to Nivolumab by Itself After Complete Surgical Removal of Stage IIIb/c/d or Stage IV MelanomaThe purpose of this study is to determine whether an investigational immunotherapy Nivolumab, when combined with Ipilimumab, is more effective than Nivolumab by itself, in…NCT03068455·Tucson, Arizona and 123 others

Active not recruitingSafety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)This 2-part study will evaluate the safety and efficacy of pembrolizumab (MK-3475) compared to placebo in participants with surgically resected high-risk Stage II melanoma.NCT03553836·Tucson, Arizona and 158 others

CompletedTicilimumab (CP-675,206) in Treating Patients With Stage IIIC or Stage IV MelanomaRATIONALE: Monoclonal antibodies, such as ticilimumab (CP-675,206), can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00471887·Los Angeles, California

CompletedIrofulven in Treating Patients With Stage IV MelanomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00005968·Santa Monica, California and 4 others

CompletedAnti-Tumor Activity Of SB-485232 In Patients With Previously Untreated Metastatic MelanomaThis Phase II study is designed to evaluate the anti-tumor activity of three dose groups of SB-485232 (0.01, 0.1, and 1.0 mg/kg/day) administered intravenously as a single agent…NCT00107718·Los Angeles, California and 19 others

TerminatedPV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous MelanomaThis is an international multicenter, open-label, randomized controlled trial (RCT) of single-agent intralesional PV-10 versus systemic chemotherapy or intralesional oncolytic…NCT02288897·San Diego, California and 22 others

CompletedNonmyeloablative Allogeneic TransplantAllogeneic transplant from a matched sibling for the treatment of a variety of illnesses including bone marrow failure states, leukemias, myelodysplastic or myeloproliferative…NCT01272817·La Jolla, California

CompletedA Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced solid tumors where the efficacy of PD-1 inhibitors has…NCT03679767·Fresno, California and 51 others

UnknownCharacterization of the Melanoma-Specific Immune ResponseThe aim of this study is to study T-cells. Blood will be collected and the samples will be used to generate T cell clones.NCT00368615·Sacramento, California

Active not recruitingIpilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies ipilimumab to see how well it works compared to high-dose interferon alfa-2b in treating patients with high-risk stage III-IV melanoma that…NCT01274338·Birmingham, Alabama and 936 others

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