Lupus Clinical Trials in Philadelphia

Showing 161-180 of 258 trials

Mild Cognitive Impairment and Obstructive Sleep Apnea

NCT01482351

Obstructive sleep apnea (OSA) has been linked to increased risk for Alzheimer's disease (AD), but little prospective evidence exists on the effects of OSA treatment in preclinical AD. The objective was to determine if CPAP treatment adherence, controlling for baseline differences, predicts cognitive and everyday function after 1 year in older adults with MCI and to determine effect sizes for a larger trial. The aim of the Mild Cognitive Impairment and Obstructive Sleep Apnea (Memories 1) trial was to determine whether CPAP treatment adherence, controlling for any baseline differences in OSA severity, ApoE4, and other previously identified demographic and patient factors, might predict cognitive and everyday function after 1 year in older adults with amnestic MCI.

Obstructive Sleep ApneaMild Cognitive Impairment

George Mason University54 participantsStarted Sep 2012

Abington, Pennsylvania, United States • Philadelphia, Pennsylvania, United States • Fairfax, Virginia, United States

COMPLETEDPhase 3< 1 mile

Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus

NCT01262365

The primary objective of the study is to confirm the clinical efficacy of epratuzumab in the treatment of subjects with Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

UCB Pharma793 participantsStarted Dec 2010

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Escondido, California, United States +138 more locations

Mild Cognitive Impairment and Obstructive Sleep Apnea

Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus

Lupus Trials in Other Cities

Improving Quality of Life for African American Female Adolescents With Lupus

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea

The POSAtive Study: Study for the Treatment of Positional Obstructive Sleep Apnea

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus (SLE)

Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)

A Study of Tabalumab (LY2127399) Using Two Different Injection Methods in Participants With Lupus

A Phase 2B Open-Label, Single-Arm, Repeat-Dose Study to Evaluate the Reliability of an Autoinjector

Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor

Dose Ranging Study of Brentuximab Vedotin in Adults With Lupus

A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus

A Phase II Study to Evaluate Safety and Efficacy of ALX-0061 in Subjects With Systemic Lupus Erythematosus

Evaluation of Vestibular Stimulation to Help Occasional Sleeplessness

A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE)

Non-Inferiority Study of the FRESCA Mask Versus Existing CPAP Mask for Treatment of Obstructive Sleep Apnea

Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

Unrecognised Obstructive Sleep Apnea Study

Immunogenicity and Safety of GSK Biologicals' Combined Measles-mumps-rubella Vaccine in Volunteers, Seven Years of Age and Older

Other Conditions in Philadelphia