Lupus Clinical Trials in Philadelphia

Showing 101-120 of 134 trials

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

NCT00371293

Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person's breathing is restricted during sleep. Obese individuals with OSA are at an increased risk of inflammation and heart conditions, but it is unknown whether this risk is related to the effects of OSA or obesity. This study will evaluate whether OSA or obesity plays the primary role in inflammation related to heart disease. The study will also determine the independent effects of OSA and obesity on insulin resistance and blood vessel function.

Sleep Apnea SyndromesInflammation

University of Pennsylvania181 participantsStarted Sep 2006

Philadelphia, Pennsylvania, United States • Philadelphia, Pennsylvania, United States

COMPLETEDPHASE2< 1 mile

Effects of Melatonin on Insomnia Symptoms in Older Adults

NCT00230737

This study will determine whether melatonin tablets will increase the sleep of older adults with insomnia.

Sleep Initiation and Maintenance Disorders

Nalaka Gooneratne27 participantsStarted Oct 2004

Philadelphia, Pennsylvania, United States

COMPLETED< 1 mile

A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers

NCT02034344

The purpose of this study is to obtain skin, blood, and urine samples from patients with active cutaneous lupus lesions and from healthy participants.

Lupus Erythematosus, CutaneousLupus Erythematosus, SystemicLupus Erythematosus, Discoid+1 more

Janssen Research & Development, LLC77 participantsStarted Oct 2013

La Jolla, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +18 more locations

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

Effects of Melatonin on Insomnia Symptoms in Older Adults

A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers

Lupus Trials in Other Cities

Telemedici ne Management of Veterans With Newly Diagnosed Obstructiv e Sleep Apnea (OSA)

Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02

Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Lesions

Neurobehavioral Effects of Partial Sleep Deprivation

Promoting Continuous Positive Airway Pressure (CPAP) Adherence

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

Study of DTap-IPV Compared to DAPTACEL® and IPOL® as the 5th Dose in Children 4 to 6 Years of Age

Biomarkers of Lupus Disease: Serial Biomarker Sampling in Patients With Active Systemic Lupus Erythematosus (SLE)

A Study of Belimumab in Subjects With Systemic Lupus Erythematosus

Health-related Quality of Life Measure in Pediatric Lupus

A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or Myositis

The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus Erythematosus

Study of Epratuzumab in Systemic Lupus Erythematosus

Functional MRI in Lupus Nephritis

Safety Study of AMG 557 in Subjects With Lupus Arthritis

Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment

Other Conditions in Philadelphia