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Clareo Health | Lupus Clinical Trials in Philadelphia | 53 Studies

Clinical Trials LupusPhiladelphia

Lupus Clinical Trials in Philadelphia

Find 53 clinical trials for lupus near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lupus trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 21-40 of 53 trials

TerminatedA Study of Ustekinumab in Participants With Active Systemic Lupus ErythematosusThe purpose of this study is to evaluate the efficacy of ustekinumab in participants with active systemic lupus erythematosus (SLE) who have not adequately responded to one or…NCT03517722·Anniston, Alabama and 203 others

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Data from ClinicalTrials.govTerms

CompletedA Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus ErythematosusThe purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long…NCT04294667·Birmingham, Alabama and 176 others

Active not recruitingProgram to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus ErythematosusSystemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems.NCT05843643·Chandler, Arizona and 368 others

Active not recruitingA Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)The purpose of this study is to evaluate the efficacy, safety and drug levels of CC-97540 in participants with active systemic lupus erythematosus (SLE) including lupus nephritis…NCT07015983·Phoenix, Arizona and 96 others

RecruitingCD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for LupusThis is a single-center, single-arm, open-label phase 1/2 study of CART19 in children and young adults with refractory Systemic lupus erythematosus (SLE), including both patients…NCT06839976·Philadelphia, Pennsylvania

RecruitingTesting an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVOThis phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum…NCT03816345·Birmingham, Alabama and 51 others

CompletedSpine Quantitative Computed Tomography (QCT) for the Assessment of Osteoporosis on ChildrenThe purpose of this study is to compare healthy children to children who have systemic lupus erythematosus (SLE).NCT01330368·Philadelphia, Pennsylvania

CompletedSafety and Efficacy Study of LJP 394 (Abetimus Sodium) to Treat Lupus Kidney DiseaseThe purpose of this study is to determine whether LJP 394 (abetimus sodium) is safe and effective in delaying and reducing renal flares in patients with lupus nephritis.NCT00035308·Birmingham, Alabama and 81 others

TerminatedSafety Study of AMG 811 in Subjects With Discoid Lupus ErythematosusThis is a multi-center, randomized, double-blind, placebo-controlled, two-period, crossover study in which approximately 20 subjects with Discoid Lupus Erythematosus will be…NCT01164917·Santa Monica, California and 7 others

RecruitingA Phase 1 Study of FT819 in B-cell Mediated Autoimmune DiseaseThis is a phase 1 study designed to evaluate the safety, pharmacokinetics (PK), and anti-B-cell activity of FT819 following treatment with or without auxiliary medicinal product…NCT06308978·Beverly Hills, California and 20 others

CompletedLong Term Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus ErythematosusThe purpose of this study is to characterise long-term safety and tolerability of intravenous anifrolumab.NCT02794285·Birmingham, Alabama and 174 others

CompletedA Pilot Study of CC-220 to Treat Systemic Lupus Erythematosus.The purpose of this study is to determine whether CC-220 is effective for the treatment of skin, joint and serological manifestations of systemic lupus erythematosus.NCT02185040·Birmingham, Alabama and 34 others

CompletedRandomized Study of Oral Contraceptives or Hormone Replacement Therapy in Women With Systemic Lupus ErythematosusOBJECTIVES: I.NCT00006133·Birmingham, Alabama and 16 others

CompletedA Phase 2a, Efficacy and Safety Study of Ustekinumab in Systemic Lupus ErythematosusThe purpose of this study is to evaluate the efficacy of ustekinumab as measured by a reduction in disease activity for subjects with active Active Systemic Lupus Erythematosus…NCT02349061·Huntsville, Alabama and 42 others

Active not recruitingPhase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus ErythematosusThe purpose of this study is to assess the clinical efficacy, safety, PK, and PD of multiple dose levels of ESK-001 compared with placebo in adult patients with SLE.NCT05966480·Anniston, Alabama and 168 others

Active not recruitingA Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)This is a prospective, open-label, single arm 3-year clinical study to describe the short-term and long-term efficacy and safety of belimumab in participants with autoantibody…NCT06411249·Anniston, Alabama and 108 others

RecruitingA Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 ImmunosuppressantsThe purpose of this study is to characterize the efficacy and safety of current standard of care treatment options in participants with active systemic lupus erythematosus (SLE…NCT07175285·La Jolla, California and 65 others

Active not recruitingA 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus ErythematosusIn this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with cutaneous lupus erythematosus (CLE).NCT05531565·Anniston, Alabama and 314 others

TerminatedVitamin D3 Treatment in Pediatric Systemic Lupus ErythematosusThe primary objective of this study is to evaluate the effects of 18 weeks of high-dose vitamin D3 supplementation compared with standard-dose vitamin D3 supplementation on immune…NCT01709474·Los Angeles, California and 12 others

CompletedA Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus ErythematosusThe purpose of this Phase 2, multicenter, randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of an oral treatment regimen of CC-220 versus…NCT03161483·Tuscaloosa, Alabama and 183 others

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