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Clareo Health | Lung Cancer Clinical Trials in Tennessee | 898 Studies

Clinical Trials Lung CancerTennessee

Lung Cancer Clinical Trials in Tennessee

Find 898 clinical trials for lung cancer near Tennessee. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 81-100 of 898 trials

CompletedStudy of XL281 in Adults With Solid TumorsThe purpose of this study is to determine the safest dose of the multiple Raf kinase inhibitor (including c-Raf, B-Raf, and the activated mutant B-RafV600E) XL281, how often it…NCT00451880·Scottsdale, Arizona and 5 others Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid TumorsThis is a phase I, First-in-Human (FIH), open-label study to evaluate the safety, tolerability, pharmacokinetic (PK) profile, and preliminary efficacy of AB248 as monotherapy OR…NCT05653882·Duarte, California and 19 others

CompletedS0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone MetastasesRATIONALE: Gathering information about how often osteonecrosis of the jaw occurs in patients receiving zoledronic acid for bone metastases may help doctors learn more about the…NCT00874211·Anniston, Alabama and 452 others

Active not recruitingAssess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLCThe purpose of this study is to assess the efficacy of selumetinib in combination with docetaxel (75mg/m2) vs placebo in combination with docetaxel (75mg/m2) in patients with…NCT01933932·Aurora, Colorado and 196 others

TerminatedMP0250 DARPin® Protein Plus Osimertinib in Patients With EGFR-mutated NSCLCThe purpose of this study is to assess the anti-tumor efficacy, safety, tolerability, pharmacokinetics (PK), immunogenicity and biological activity of the MP0250 DARPin® drug…NCT03418532·Scottsdale, Arizona and 9 others

TerminatedAn Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung CancerThe purpose of this study is to determine whether Nivolumab, in combination with other therapies, is effective in patients with advanced Non-Small Cell lung cancerNCT02750514·Duarte, California and 49 others

TerminatedRandomized Ph 2 Trial Of Paclitaxel/Carboplatin /Bevacizumab + PF-3512676 And P/C/B Alone In Advanced Nonsquamous NSCLCTo assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel, carboplatin and bevacizumab as first-line treatment in patients with locally advanced…NCT00313768·Bessemer, Alabama and 28 others

CompletedAn Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced CancersA study to evaluate the safety of Nivolumab given in combination with Ipilimumab in patients with advanced cancers.NCT02869789·Birmingham, Alabama and 135 others

TerminatedClinical Study of Antibody-Drug Conjugate MYTX-011 in Subjects With Non-Small Cell Lung CancerThis is a Phase I open label multi-center study to evaluate the safety, tolerability, pharmacokinetics and preliminary effectiveness of the investigational drug MYTX-011 in…NCT05652868·La Jolla, California and 54 others

CompletedA Randomized Phase 3 Trial of Pemetrexed and Cisplatin Versus Gemcitabine and Cisplatin in Patients With Locally Advanced or Metastatic Non Small Cell Lung CancerThis study is a randomized Phase 3 study comparing pemetrexed and cisplatin combination to gemcitabine and cisplatin for the treatment of Non Small Cell Lung Cancer (NCSLC).NCT00087711·Sacramento, California and 133 others

CompletedA Study of BIND-014 Given to Patients With Advanced or Metastatic CancerThe goal of this Phase 1 clinical research study is to find the highest safe dose of BIND-014 that can be given in the treatment of patients with advanced or metastatic cancer.NCT01300533·Scottsdale, Arizona and 5 others

CompletedA Phase II Study of Epothilone Analog BMS-247550 in Patients With Non-Small Cell Lung Cancer Who Have Failed First Line Platinum Based ChemotherapyThe purpose of this clinical research study is to learn if BMS-247550 can shrink or slow the growth of the cancer in patients with non-small cell lung cancer who have failed…NCT00035516·Birmingham, Alabama and 15 others

Active not recruitingPredicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer TreatmentsThe PROPHETIC study is a prospective, multi-center, international clinical study aimed at developing an algorithm to predict patient outcomes.NCT04056247·Birmingham, Alabama and 40 others

Active not recruitingTesting the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung CancerThis phase III trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer.NCT04214262·Anchorage, Alaska and 389 others

RecruitingRinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)This study will test the safety, including side effects, and determine the characteristics of a drug called Rina-S in participants with solid tumors.NCT05579366·Phoenix, Arizona and 66 others

CompletedAtezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 InhibitorThis is a Phase II, two part trial (A and B), open label study of Atezolizumab and tiragolumab, or atezolizumab combined with SOC chemotherapy in patients with NSCLC or advanced…NCT03977467·Fort Myers, Florida and 6 others

CompletedEfficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior ChemotherapyTo determine if ZD6474 a new investigational drug, is effective in treating Non Small Lung Cancer and if so, how it compares with another type of anti cancer therapy chemotherapy…NCT00364351·Berkeley, California and 152 others

TerminatedConcordance of Key Actionable Genomic Alterations as Assessed in Tumor Tissue and Plasma in Non Small Cell Lung CancerA study to determine the concordance of key actionable genomic alterations as assessed in tumor tissue and plasma from patients with non small cell lung carcinoma (NSCLC)NCT02762877·Torrance, California and 21 others

Active not recruitingCAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLCThe purpose of this clinical trial is to evaluate the effects of adding CAN-2409 + prodrug for stage III/IV NSCLC patients who are on standard of care first line immune checkpoint…NCT04495153·Phoenix, Arizona and 13 others

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