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Clareo Health | Lung Cancer Clinical Trials in Tennessee | 898 Studies

Clinical Trials Lung CancerTennessee

Lung Cancer Clinical Trials in Tennessee

Find 898 clinical trials for lung cancer near Tennessee. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Tennessee

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 321-340 of 898 trials

CompletedA Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsThis research study is done to test how well different types of cancer respond to the drug called larotrectinib.NCT02576431·Palo Alto, California and 97 others

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Data from ClinicalTrials.govTerms

TerminatedAzacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)This is an open-label, Phase 1/2 study in subjects with advanced or metastatic solid tumors.NCT02959437·Duarte, California and 11 others

TerminatedA Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing CancerTC-510 is a novel cell therapy that consists of autologous genetically engineered T cells expressing two synthetic constructs: first, a single-domain antibody that recognizes…NCT05451849·San Franciso, California and 6 others

CompletedPulmonary Physiology and Systemic Inflammatory in EO Pulmonary Events With Brigatinib Use in NSCLC and Other DiseasesTo estimate the incidence of Early Onset Pulmonary Events (EOPEs), defined as the proportion of participants with a peak reduction in DLCO of 20% or greater after commencing…NCT03389399·Aurora, Colorado and 4 others

TerminatedAfatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung CancerThis phase I trial studies the side effects and best dose of afatinib and necitumumab and to see how well they work in treating patients with EGFR mutation positive non-small cell…NCT03054038·Duarte, California and 2 others

TerminatedStudy of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung CancerTo compare the efficacy of pegilodecakin in combination with pembrolizumab versus pembrolizumab alone in participants with metastatic non-small cell lung cancer as measured by…NCT03382899·Huntsville, Alabama and 73 others

Active not recruitingA Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological FeaturesThis is a Phase III, randomised, open-label, multicentre, global study assessing the efficacy and safety of adjuvant Dato-DXd in combination with rilvegostomig compared with SoC…NCT06564844·Tucson, Arizona and 89 others

CompletedZoledronate in Treating Patients With Solid Tumors That Have Spread to the BoneRATIONALE: Zoledronate may help to relieve some of the symptoms caused by bone metastases.NCT00003884·Birmingham, Alabama and 54 others

CompletedPhase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung CancerThis is a Phase II, open-label, multicenter, multi cohort, study of VS-6063 (defactinib), a focal adhesion kinase inhibitor, in patients with KRAS mutant non-small cell lung…NCT01951690·Denver, Colorado and 8 others

RecruitingTargeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer.NCT06116682·Jonesboro, Arkansas and 270 others

RecruitingA Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsThis is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in…NCT07277413·Goodyear, Arizona and 22 others

RecruitingA First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS MutationsA first in human study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of BLU-924 / SAR449336, a pan-KRAS inhibitor, in participants with advanced…NCT07629960·Sarasota, Florida and 15 others

CompletedStudy of the Glutaminase Inhibitor CB-839 in Solid TumorsMany tumor cells, in contrast to normal cells, have been shown to require the amino acid glutamine to produce energy for growth and survival.NCT02071862·San Francisco, California and 12 others

CompletedPlacebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung CancerThis is a multicenter, randomized, double-blind, placebo-controlled study of niraparib plus pembrolizumab versus placebo plus pembrolizumab as maintenance therapy in participants…NCT04475939·Fullerton, California and 187 others

TerminatedPh II of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Treatment of Non-Small Cell Lung CancerThe purpose of this study is to determine the efficacy of CT-322 comparative to bevacizumab, both in combination with carboplatin and paclitaxel in the treatment of chemonaive…NCT00850577·Tucson, Arizona and 54 others

CompletedCPG 7909 Injection in Non-Small Cell Lung CancerEligible patients will be randomized in a ratio of 2:1 to receive either chemotherapy (a taxane and a platinum compound) plus CPG 7909 Injection or chemotherapy alone.NCT00070629·Gilroy, California and 23 others

TerminatedA Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 MutationThis is a Phase 1 study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of PRT7732 in patients with select advanced or…NCT06560645·San Francisco, California and 27 others

Active not recruitingAZD9291 in Combination With Ascending Doses of Novel TherapeuticsThe purpose of this study is to determine the safety, tolerability and preliminary anti-tumour activity of AZD9291 when given together with AZD6094 or selumetinib in patients with…NCT02143466·Atlanta, Georgia and 41 others

CompletedAvelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200)The main purpose of this study was to demonstrate superiority with regard to overall survival of avelumab versus docetaxel in participants with programmed death ligand 1 (PD-L1)…NCT02395172·Tuscaloosa, Alabama and 259 others

CompletedStudy of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer (NSCLC) (CheckMate 017)The purpose of the study is to compare the overall survival of BMS-936558 as compared with Docetaxel in subjects with squamous cell non-small cell lung cancer (NSCLC), after…NCT01642004·Scottsdale, Arizona and 126 others

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