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Clareo Health | Lung Cancer Clinical Trials in Tennessee | 889 Studies

Clinical Trials Lung CancerTennessee

Lung Cancer Clinical Trials in Tennessee

Find 889 clinical trials for lung cancer near Tennessee. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 181-200 of 889 trials

UnknownA Study of SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid TumorsA first-in-human (FIH) study using SBT6050 and SBT6050 in combination with PD-1 inhibitors in HER2 expressing or amplified advanced malignanciesNCT04460456·Boston, Massachusetts and 11 others CompletedA Study of Personalized Neoantigen Cancer VaccinesThe purpose of this study is 1) to evaluate the feasibility of manufacturing a patient-specific neoantigen cancer vaccine, which involves predicting the patient's neoantigens and…NCT03794128·Chicago, Illinois and 4 others TerminatedPh II Trial of Carboplatin and Pemetrexed With or Without AZD1775 for Untreated Lung CancerThe aim of this study is to combine AZD1775 with standard front-line chemotherapy in subjects with advanced NSCLC.NCT02087241·Englewood, Colorado and 7 others

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Data from ClinicalTrials.govTerms

CompletedStudy of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based TreatmentThe purpose of this clinical study is to determine the effectiveness (ability to provide beneficial treatment of the disease) and safety of pralatrexate compared to erlotinib when…NCT00606502·Bakersfield, California and 46 others

WithdrawnTesting the Use of Targeted Treatment for RET Positive Advanced Non-small Cell Lung CancerThis phase II Lung-MAP treatment trial tests whether carboplatin and pemetrexed with or without selpercatinib works to shrink tumors in patients with RET fusion-positive non-small…NCT05364645·Jonesboro, Arkansas and 264 others

TerminatedS0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone SurgeryRATIONALE: A program that includes bupropion may be more effective in helping early-stage lung cancer patients to quit smoking.NCT00032084·Anniston, Alabama and 175 others

TerminatedBasket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 MutationsThis is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in…NCT01953926·Birmingham, Alabama and 59 others

TerminatedGSK1572932A Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients With Non-Small Cell Lung CancerThe purpose of this clinical trial is to demonstrate the benefit of the immunotherapeutic product GSK1572932A when given to patients with Non-Small Cell Lung Cancer, after removal…NCT00480025·Birmingham, Alabama and 619 others

CompletedSL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or LymphomasThis is a Phase 1 first in human, open label, multi-center, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, anti-tumor activity and…NCT03894618·Nashville, Tennessee and 4 others

CompletedPhase II Trial of Carboplatin and Pemetrexed +/- OGX-427 in Untreated Stage IV Non-Squamous-Non-Small-Cell Lung CancerThis randomized phase II study will compare the efficacy and safety of the combination of carboplatin and pemetrexed with and without OGX-427 in patients with previously untreated…NCT01829113·Denver, Colorado and 15 others

CompletedA Study to Evaluate Immunotherapy Combinations in Participants With Lung CancerThis is a Phase 1/1b, multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic, and clinical…NCT03846310·Tucson, Arizona and 21 others

Terminated(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLCThis is a Phase 1/2, open-label, first-in-human (FIH) study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and anticancer activity of…NCT04862780·La Jolla, California and 25 others

CompletedA Study of Prexasertib (LY2606368) in Combination With Ralimetinib in Participants With Advanced or Metastatic CancerThe main purpose of this study is to evaluate the safety of the study drug prexasertib in combination with ralimetinib in participants with advanced or metastatic cancer.NCT02860780·Charlotte, North Carolina and 2 others

CompletedA Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced CancerThe purpose of this study is to find a recommended schedule and dose range for Emibetuzumab when given with ramucirumab that may be safely given to participants with cancer.NCT02082210·Boston, Massachusetts and 3 others

TerminatedPilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With PembrolizumabThis trial will evaluate safety and tolerability of letetresgene autoleucel (GSK3377794) with or without pembrolizumab in participants with non-small cell lung cancer.NCT03709706·Duarte, California and 30 others

CompletedErlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal CancerThis phase I trial is studying the side effects and best dose of erlotinib hydrochloride when given together with cetuximab and to see how well they work in treating patients with…NCT00397384·Nashville, Tennessee

TerminatedA Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing CancerTC-510 is a novel cell therapy that consists of autologous genetically engineered T cells expressing two synthetic constructs: first, a single-domain antibody that recognizes…NCT05451849·San Franciso, California and 6 others

CompletedM7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)The purpose of the study is to evaluate the efficacy and safety of bintrafusp alfa (M7824) compared with pembrolizumab in participants with advanced NSCLC with high PD-L1-tumor…NCT03631706·Huntsville, Alabama and 118 others

CompletedPhase 1b DV281 With an Anti-PD-1 Inhibitor in NSCLCThis open-label, multicenter, dose-escalation and expansion trial is designed to evaluate the safety and preliminary efficacy of inhaled DV281 in combination with nivolumabfor the…NCT03326752·La Jolla, California and 5 others

RecruitingSafety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung CancerThis is a Phase 2/3, multisite, randomized, open-label study in participants with first-line non-small cell lung cancer (NSCLC).NCT06712316·Birmingham, Alabama and 364 others

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