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Clareo Health | Lung Cancer Clinical Trials in Pittsburgh | 374 Studies

Clinical Trials Lung CancerPittsburgh

Lung Cancer Clinical Trials in Pittsburgh

Find 374 clinical trials for lung cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 181-200 of 374 trials

CompletedPhase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid TumorsThis is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in…NCT04344795·Aurora, Colorado and 10 others RecruitingRadiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung CancerThis study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination…NCT06686771·Phoenix, Arizona and 74 others

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Data from ClinicalTrials.govTerms

TerminatedA Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.This was a clinical study with an orally administered drug, BDTX-189 in participants with advanced solid tumors that had select mutations or alterations in human epidermal growth…NCT04209465·Scottsdale, Arizona and 37 others

CompletedDose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung CancerThe study objective is to evaluate the maximum tolerated dose, safety and efficacy of patupilone in patients with NSCLC who have progressed after prior chemotherapy.NCT00171834·Louisville, Kentucky and 3 others

CompletedIressa Expanded Access Program (EAP)A program for patients with non small cell lung cancer who may benefit from Iressa, but cannot enter another clinical trial due to them not being eligible, or for whom no trials…NCT00034879·Alabaster, Alabama and 625 others

TerminatedNivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune DiseaseThe purpose of this study is to explore the safety, tolerability and activity of Nivolumab, a PD-1 inhibitor, in cohorts of patients with autoimmune disease.NCT03656627·Chicago, Illinois and 8 others

TerminatedASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung CancerThe purpose of this study is to determine if adding ASA404 to standard chemotherapy makes the cancer treatment more effective in patients with advanced lung cancer.NCT00662597·Mobile, Alabama and 247 others

CompletedRucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)This phase II Lung-MAP trial studies how well rucaparib works in treating patients with genomic loss of heterozygosity (LOH) high and/or deleterious BRCA1/2 mutation stage IV…NCT03845296·Mobile, Alabama and 949 others

RecruitingPhase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid TumorsThis is a Phase 1, multicenter, open-label dose escalation study to determine the safety and tolerability of intratumoral (IT) injection of tolododekin alfa (ANK-101) in…NCT06171750·Bethesda, Maryland and 4 others

RecruitingStudy of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLCThe purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibitors as a monotherapy…NCT06162221·Gilbert, Arizona and 92 others

Active not recruitingA Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer.The purpose of eVOLVE-Lung02 is to test the effectiveness (efficacy) and measure the safety of volrustomig in combination with chemotherapy compared with pembrolizumab in…NCT05984277·Hot Springs, Arkansas and 246 others

Active not recruitingComparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung CancerRATIONALE: Wedge resection or segmentectomy may be less invasive types of surgery than lobectomy for non-small cell lung cancer and may have fewer side effects and improve…NCT00499330·Birmingham, Alabama and 385 others

CompletedPhase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01876 when given in combination with immune therapies in subjects with advanced or…NCT03126110·Los Angeles, California and 37 others

Active not recruitingAdjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)The optimal treatment for Stage I or Stage IIA non-small cell lung cancer (NSCLC) remains controversial.NCT01817192·Mission Viejo, California and 48 others

CompletedPrognostic Study of Metastases in Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer That Can Be Removed by SurgeryRATIONALE: Prognostic testing for early signs of metastases may help doctors detect metastases early and plan more effective treatment.NCT00003901·Mobile, Alabama and 57 others

Active not recruitingA Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid TumorsThe main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally advanced or metastatic solid…NCT06607185·Birmingham, Alabama and 44 others

CompletedThis Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.The purpose of this study is to assess the efficacy and safety of ZD6474 in patients with NSCLC after Failure of Prior Platinum-based Chemotherapy.NCT00047840·Los Angeles, California and 25 others

TerminatedA Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced CancersMulti-center, open-label, first in human Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous…NCT04025216·Phoenix, Arizona and 9 others

CompletedCombination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00041314·Birmingham, Alabama and 78 others

Active not recruitingA Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to assess the safety and efficacy of divarasib compared to locally approved KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS…NCT06497556·Gilbert, Arizona and 150 others

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