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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 755 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 755 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 621-640 of 755 trials

RecruitingA Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)The primary purpose of the study is to assess how well amivantamab in combination with lazertinib or in combination with chemotherapy works (antitumor activity) in participants…NCT06667076·Daphne, Alabama and 203 others

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Data from ClinicalTrials.govTerms

TerminatedA Study to Investigate LYL845 in Adults With Solid TumorsThis is an open-label, multi-center, dose-escalation study with expansion cohorts, designed to evaluate the safety and anti-tumor activity of LYL845, an epigenetically…NCT05573035·Sacramento, California and 17 others

TerminatedA Phase 3 Study of Ganetespib in Combination With Docetaxel Versus Docetaxel Alone in Patients With Advanced NSCLCThe purpose of this study is to determine whether combining ganetespib (STA-9090) with docetaxel is more effective than docetaxel alone in the treatment of patients with advanced…NCT01798485·Flagstaff, Arizona and 266 others

TerminatedA Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating MutationsThe purpose of the study was to evaluate the progression free survival (PFS), based on independent radiologic review (IRR), of ASP8273 compared to erlotinib or gefitinib in…NCT02588261·Beverly Hills, California and 166 others

Active not recruitingStudy of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in META phase 1/2, first-in-human, open-label study of the safety, tolerability, PK, and efficacy of the novel MET/CSF1R/SRC inhibitor TPX-0022 in adult subjects with advanced or…NCT03993873·La Jolla, California and 23 others

TerminatedRadiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung CancerThis randomized phase III trial is studying whole-brain radiation therapy and stereotactic radiosurgery with or without temozolomide or erlotinib to see how well they work…NCT00096265·Scottsdale, Arizona and 82 others

CompletedCarboplatin, Abraxane, and Bevacizumab in Previously Untreated Patients With Advanced Non-Small Cell Lung CancerThe purpose of this research study is to learn more about whether the combination of drugs carboplatin, Abraxane and Avastin helps treat non-small cell lung cancer (NSCLC).NCT00642759·Boston, Massachusetts and 1 other

RecruitingStudy of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of RMC-5127 as a monotherapy and in combination with…NCT07349537·New Haven, Connecticut and 8 others

CompletedGSK3174998 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors (ENGAGE-1)This is a first time in human (FTIH), open-label, non-randomized, multicenter study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and…NCT02528357·Boston, Massachusetts and 7 others

RecruitingMOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid TumorsThe main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in…NCT06586515·Duarte, California and 51 others

RecruitingA Phase 1/1b Study of IAM1363 in HER2 CancersThis is a Phase 1/1b open-label, multi-center dose escalation and dose optimization study designed to evaluate the safety and preliminary efficacy of IAM1363 in participants with…NCT06253871·La Jolla, California and 52 others

Active not recruitingA Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung CancerThis study will evaluate REGN5093 for the treatment of Non-Small Cell Lung Cancer (NSCLC) with MET alteration.NCT04077099·Orange, California and 28 others

WithdrawnA Study of LY3200882 and Pembrolizumab in Participants With Advanced CancerThe main purpose of this study is to see if the drug LY3200882 which is an inhibitor of transforming growth factor-β (TGFβ) receptor 1 in combination with pembrolizumab is safe…NCT04158700·Boston, Massachusetts and 5 others

UnknownSafety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced MalignanciesThe primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies…NCT04137900·Birmingham, Alabama and 23 others

CompletedComprehensive Genomic Analysis in Tissue and Blood Samples From Young Patients With Lung CancerThis research trial studies genomic analysis in tissue and blood samples from young patients with lung cancer.NCT02273336·Los Angeles, California and 1 other

RecruitingPhase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid TumorsPhase I Study, a master protocol to investigate TCR-Engineered T cells recognizing KRAS mutations in adult subjects with Unresectable, Advanced, and/or Metastatic Solid Tumors.NCT06218914·Duarte, California and 17 others

CompletedLume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLCThe trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo (inactive capsule) plus standard pemetrexed…NCT00806819·Downy, California and 162 others

TerminatedIMM60 and Pembrolizumab in Melanoma and NSCLCThe goal of this clinical trial is to learn about IMM60 with or without pembrolizumab in participants with advanced melanoma or non-small cell lung cancer.NCT05709821·Los Angeles, California and 13 others

Active not recruitingTepotinib Phase II in NSCLC Harboring MET Alterations (VISION)This study looked at how effective the study drug (tepotinib) was at stopping the growth and spread of lung cancer.NCT02864992·Duarte, California and 175 others

RecruitingBeamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD MutationsBeamion LUNG-3 study evaluates whether zongertinib, an oral HER2-targeted treatment, can improve outcomes compared with standard adjuvant treatment in adults with completely…NCT07195695·Fresno, California and 201 others

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Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma