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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 759 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 759 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 461-480 of 759 trials

RecruitingPhase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or MetastaticThis study is a first-in-human (FIH) Phase 1 open-label, multicenter study including three parts: * Part 1A is a dose escalation of STRO-006 monotherapy in selected tumor types…NCT07807345·Orlando, Florida and 5 others CompletedSurgery With or Without Internal Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung CancerThis randomized phase III trial studies surgery and internal radiation therapy to see how well they work compared to surgery alone in treating patients with stage I non-small cell…NCT00107172·Scottsdale, Arizona and 37 others

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Data from ClinicalTrials.govTerms

CompletedCombination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial)This phase II LUNG-MAP treatment trial studies how well combination treatment (talazoparib plus avelumab) works in treating patients with non-squamous non-small cell lung cancer…NCT04173507·Mobile, Alabama and 324 others

CompletedCetuximab and Vinorelbine in Elderly Subjects With Lung CancerThe purpose of this study is it to determine how well patients with non-small cell lung cancer respond to cetuximab plus vinorelbine.NCT00165334·Boston, Massachusetts and 2 others

RecruitingA Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP DeletionThe purpose of this study is to compare the clinical benefit of the combination of Navlimetostat (BMS-986504) (a selective MTA-cooperative inhibitor of PRMT5) plus pembrolizumab…NCT07063745·Anchorage, Alaska and 320 others

CompletedS0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung CancerRATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00661193·Little Rock, Arkansas and 123 others

CompletedStudy of Plasma NGS for Assessment, Characterization, Evaluation of Patients With ALK ResistanceALK-positive lung cancer is a subtype of lung cancer which carries a change in a gene called ALK (anaplastic lymphoma kinase).NCT03833934·Boston, Massachusetts

Active not recruitingTesting the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)This phase II/III Lung-MAP trial studies how well immunotherapy treatment with N-803 (ALT-803) and pembrolizumab working in treating patients with non-small cell lung cancer that…NCT05096663·Birmingham, Alabama and 349 others

RecruitingA Study of ERAS-0015 in Patients With Advanced or Metastatic Solid TumorsThe main purpose of the study is to assess whether the study drug, ERAS-0015, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with…NCT06983743·Santa Rosa, California and 12 others

RecruitingNeladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLCMulticenter, randomized, controlled, open-label, Phase 3 study designed to demonstrate that neladalkib (NVL-655) is superior to alectinib in prolonging progression-free survival…NCT06765109·Glendale, Arizona and 158 others

CompletedAn Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)The purpose of this study is to show that Nivolumab will improve progression free survival in subjects with strongly Stage IV or Recurrent PD-L1+ non-small cell lung cancer when…NCT02041533·Mobile, Alabama and 140 others

TerminatedA Study of Varlilumab and Atezolizumab in Patients With Advanced CancerThis is a study to determine the clinical benefit (how well the drug works), safety and tolerability of combining varlilumab and atezolizumab.NCT02543645·San Francisco, California and 3 others

CompletedDose Range Study of Anamorelin in Patients With Non-small Cell Lung CancerThe purpose of this study is to evaluate doses of anamorelin for safety and efficacy in patients with non-small cell lung cancer.NCT00622193·Little Rock, Arkansas and 32 others

CompletedPhase 1b/2 Study of Retaspimycin HCl (IPI-504) in Combination With Everolimus in KRAS Mutant Non-small Cell Lung CancerStudy IPI-504-15 is a Phase 1b/2 clinical trial to evaluate the safety and efficacy of retaspimycin HCl (IPI-504) plus everolimus in patients with KRAS mutant Non-small Cell Lung…NCT01427946·Aurora, Colorado and 4 others

Active not recruitingDose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor) monotherapy in adult…NCT05462717·Springdale, Arkansas and 63 others

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

Active not recruitingA Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)The primary purpose of this study is to determine the antitumor activity of enfortumab vedotin as measured by confirmed objective response rate (ORR) per RECIST v1.1.NCT04225117·Tucson, Arizona and 38 others

Active not recruitingStudy of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung CancerThis is an open label multi center trial to determine the safety and efficacy of ceritinib in combination with nivolumab in ALK-positive NSCLC patientsNCT02393625·Scottsdale, Arizona and 11 others

TerminatedPhase II Study of Therapy With PS 341 in Patients With Advanced Stage Non Small Cell Lung CancerThe purpose of this study is to develop new treatments that will hopefully result in the relief of symptoms and prolongation of life.NCT00200382·Fitchburg, Massachusetts and 4 others

Active not recruitingStudy of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in META phase 1/2, first-in-human, open-label study of the safety, tolerability, PK, and efficacy of the novel MET/CSF1R/SRC inhibitor TPX-0022 in adult subjects with advanced or…NCT03993873·La Jolla, California and 23 others

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Other Conditions in Massachusetts

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