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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 755 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 755 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 261-280 of 755 trials

Active not recruitingELVN-002 in HER2 Mutant Non-Small Cell Lung CancerThe goal of this clinical trial is to test ELVN-002 in people with cancers that have an abnormal HER2 gene.NCT05650879·Aurora, Colorado and 38 others

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Data from ClinicalTrials.govTerms

CompletedSym015 (Anti-MET) in Patients With Advanced Solid Tumor MalignanciesThis is the first study to test Sym015 in humans.NCT02648724·Aurora, Colorado and 26 others

CompletedA Dose Escalation Study of ASP8273 in Subjects With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) MutationsThe purpose of this study is to assess the safety and tolerability of ASP8273 and to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D).NCT02113813·Washington D.C., District of Columbia and 11 others

CompletedA Study of PDR001 in Combination With LCL161, Everolimus or PanobinostatThe purpose of this study was to combine the PDR001 checkpoint inhibitor with several agents with immunomodulatory activity to identify the doses and schedule for combination…NCT02890069·Santa Monica, California and 24 others

CompletedA Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) InhibitorsThe primary purpose of this study is to determine the differences in PFS for participants who have been receiving brigatinib as ALK inhibitor therapy for ALK+NSCLC compared to…NCT03546894·Maynard, Massachusetts

CompletedEfficacy and Safety of Pembrolizumab (MK-3475) With Lenvatinib (E7080/MK-7902) vs. Docetaxel in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease (PD) After Platinum Doublet Chemotherapy and Immunotherapy (MK-7902-008/E7080-G000-316/LEAP-008)This study will evaluate the efficacy and safety of pembrolizumab (MK-3475) with lenvatinib (E7080/MK-7902) vs. docetaxel in participants with metastatic non-small cell lung…NCT03976375·Bakersfield, California and 142 others

CompletedPlacebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung CancerThis is a multicenter, randomized, double-blind, placebo-controlled study of niraparib plus pembrolizumab versus placebo plus pembrolizumab as maintenance therapy in participants…NCT04475939·Fullerton, California and 187 others

Active not recruitingDurvalumab With Stereotactic Body Radiation Therapy (SBRT) vs Placebo With SBRT in Early Stage Unresected Non-small Cell Lung Cancer (NSCLC) Patients/ Osimertinib Following SBRT in Patients With Early Stage Unresected NSCLC Harboring an EGFR MutationThis is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in…NCT03833154·Tuscaloosa, Alabama and 208 others

CompletedSafety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor CancerA multi-center Phase 1b/2 study testing the combination of AMG 820 and pembrolizumab in subjects with select advanced solid tumors.NCT02713529·Atlanta, Georgia and 14 others

Terminated89Zr-girentuximab for PET Imaging of CAIX Positive Solid TumorsA prospective, open-label, phase 2 study to explore CAIX expression through 89Zirconium-labelled girentuximab deferoxamine (89Zr-girentuximab) PET/CT imaging in patients with…NCT05563272·Los Angeles, California and 9 others

CompletedVopratelimab and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Subjects With NSCLC or Urothelial CancerJTX-2011-201 is a Phase 2, open label clinical study of vopratelimab (JTX-2011) and ipilimumab in adult subjects with non-small cell lung cancer (NSCLC) or urothelial cancer to…NCT03989362·Beverly Hills, California and 20 others

RecruitingA Study of STRO-004 in Adults With Refractory/Recurrent Metastatic CancerThis is a study to evaluate the safety and preliminary anti-tumor activity of STRO-004 in adults with metastatic cancer.NCT07227168·San Diego, California and 8 others

CompletedStudy of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)Researchers are looking for new ways to treat people with locally advanced non-small cell lung cancer (NSCLC).NCT05298423·Long Beach, California and 159 others

CompletedPhase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in METMGCD265 is an orally administered receptor tyrosine kinase inhibitor that targets MET and other receptors.NCT02544633·Birmingham, Alabama and 93 others

RecruitingA Study of SGN-CEACAM5C in Adults With Advanced Solid TumorsThis clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood.NCT06131840·Phoenix, Arizona and 47 others

Active not recruitingTargeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial)This phase II LUNG-MAP treatment trial studies how well selpercatinib works in treating patients with RET fusion-positive non-small cell lung cancer that is stage IV or has come…NCT04268550·Fairbanks, Alaska and 305 others

TerminatedTrial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung CancerTo assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel/carboplatin chemotherapy as first-line treatment in patients with locally advanced or…NCT00254891·Little Rock, Alaska and 190 others

Active not recruitingPhase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR MutationsBDTX-1535-101 is an open-label, Phase 1 dose escalation and Phase 2 multiple cohort study designed to evaluate the safety, pharmacokinetics (PK), optimal dosage, central nervous…NCT05256290·Birmingham, Alabama and 24 others

No longer availableExpanded Treatment Protocol With LDK378 in ALK(+) NSCLCNovartis-sponsored, open-label, multi-center, interventional ETP to provide LDK378 to patients with ALK (+)NSCLC, who have been pre-treated with an ALK inhibitor; except in…NCT01947608·Chandler, Arizona and 49 others

RecruitingAVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)This study, the first clinical trial of AVZO-1418, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity…NCT07038343·Gilbert, Arizona and 18 others

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