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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 759 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 759 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 261-280 of 759 trials

TerminatedA Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating MutationsThe purpose of the study was to evaluate the progression free survival (PFS), based on independent radiologic review (IRR), of ASP8273 compared to erlotinib or gefitinib in…NCT02588261·Beverly Hills, California and 166 others

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Data from ClinicalTrials.govTerms

Active not recruitingNutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung CancerThe NutriCare study aims to develop, implement, and evaluate the efficacy of an innovative intervention strategy (medically tailored meals plus nutrition counseling) to integrate…NCT04986670·Boston, Massachusetts and 3 others

CompletedA Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)This study was to assess the antitumor activity, safety, tolerability, and pharmacokinetics (PK) of the Mesenchymal-epithelial Transition Factor (MET) inhibitor tepotinib combined…NCT03940703·Yuma, Arizona and 178 others

RecruitingA Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)This is a trial to evaluate the efficacy, safety, and tolerability of adagrasib plus pembrolizumab plus platinum-doublet chemotherapy versus placebo plus pembrolizumab plus…NCT06875310·Birmingham, Alabama and 316 others

CompletedA Phase 1/2 Study Evaluating ABT-751 in Combination With Alimta in Advanced Non-Small Cell Lung CancerTo determine the efficacy of ABT-751 when administered in combination with standard pemetrexed in subjects with advanced or metastatic NSCLC.NCT00297089·Fayetteville, Arkansas and 47 others

RecruitingA Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid TumorsThe primary purpose of this study is to evaluate the safety and tolerability, determine the maximally tolerated dose (MTD) and/or recommended Phase 2 dose(s) (RP2D) of PT0511 in…NCT07300150·Boston, Massachusetts and 8 others

CompletedA Study of Avutometinib (VS-6766) + Defactinib in Recurrent KRAS G12V, Other KRAS and BRAF Non-Small Cell Lung CancerThis study will assess the safety and efficacy of avutometinib (VS-6766) monotherapy or VS-6766 in combination with defactinib in subjects with recurrent Non-small cell lung…NCT04620330·Duarte, California and 44 others

TerminatedGemcitabine Hydrochloride or Pemetrexed Disodium and Carboplatin With or Without Celecoxib in Treating Patients With Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or…NCT01041781·Anniston, Alabama and 399 others

CompletedA Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsThis research study is done to test how well different types of cancer respond to the drug called larotrectinib.NCT02576431·Palo Alto, California and 97 others

CompletedPF-00299804 As A Single Agent, In Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Chemotherapy And ErlotinibTo assess the antitumor efficacy measured by the objective response rate of oral PF-00299804 taken daily, as single agent in patients with advanced NSCLC who failed at least one…NCT00548093·Duarte, California and 18 others

CompletedZoledronate in Treating Patients With Solid Tumors That Have Spread to the BoneRATIONALE: Zoledronate may help to relieve some of the symptoms caused by bone metastases.NCT00003884·Birmingham, Alabama and 54 others

RecruitingTargeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer.NCT06116682·Jonesboro, Arkansas and 270 others

CompletedStudy of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)Researchers are looking for new ways to treat people with locally advanced non-small cell lung cancer (NSCLC).NCT05298423·Long Beach, California and 159 others

RecruitingA First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS MutationsA first in human study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of BLU-924 / SAR449336, a pan-KRAS inhibitor, in participants with advanced…NCT07629960·Sarasota, Florida and 15 others

CompletedRadiation Therapy in Preventing Central Nervous System (CNS) Metastases in Patients With Non-Small Cell Lung CancerRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00048997·Phoenix, Arizona and 13 others

CompletedStudy of the Glutaminase Inhibitor CB-839 in Solid TumorsMany tumor cells, in contrast to normal cells, have been shown to require the amino acid glutamine to produce energy for growth and survival.NCT02071862·San Francisco, California and 12 others

Active not recruitingELVN-002 in HER2 Mutant Non-Small Cell Lung CancerThe goal of this clinical trial is to test ELVN-002 in people with cancers that have an abnormal HER2 gene.NCT05650879·Aurora, Colorado and 38 others

CompletedPlacebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung CancerThis is a multicenter, randomized, double-blind, placebo-controlled study of niraparib plus pembrolizumab versus placebo plus pembrolizumab as maintenance therapy in participants…NCT04475939·Fullerton, California and 187 others

Active not recruitingA Study of Abemaciclib (LY2835219) in Participants With Non-Small Cell Lung Cancer or Breast CancerThe main purpose of this study is to evaluate the safety and efficacy of abemaciclib in combination with pembrolizumab in participants with advanced non-small cell lung cancer…NCT02779751·Springdale, Arkansas and 23 others

TerminatedSurgery With or Without Internal Radiation Therapy Compared With Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Stage I Non-Small Cell Lung CancerRATIONALE: Surgery with or without internal radiation therapy may be an effective treatment for non-small cell lung cancer.NCT01336894·Birmingham, Alabama and 52 others

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