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Clareo Health | Lung Cancer Clinical Trials in Detroit | 433 Studies

Clinical Trials Lung CancerDetroit

Lung Cancer Clinical Trials in Detroit

Find 433 clinical trials for lung cancer near Detroit, Michigan. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Detroit

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 401-420 of 433 trials

TerminatedPemetrexed Disodium, Gemcitabine, and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung CancerRATIONALE: Pemetrexed disodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00438204·Ann Arbor, Michigan and 1 other CompletedA Drug-Interaction Study of Necitumumab (IMC-11F8) in Combination With Gemcitabine-CisplatinThe purpose of this study is to investigate the pharmacokinetics (PK) of necitumumab in combination with gemcitabine-cisplatin in participants with advanced malignant solid tumors…NCT01606748·Scottsdale, Arizona and 3 others

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Data from ClinicalTrials.govTerms

Active not recruitingPhase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)This is a Phase 1b/2 study evaluating the anti-PD1 antibody, cemiplimab, in combination with either S095018 (anti-TIM3 antibody), S095024 (anti-CD73 antibody), or S095029…NCT06162572·Detroit, Michigan and 55 others

CompletedA Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumors (ARTISTRY-2)This study will characterize the safety and tolerability and identify the recommended Phase 2 dose (RP2D) of subcutaneous (SC) ALKS 4230 as monotherapy and in combination with…NCT03861793·Los Angeles, California and 47 others

CompletedS0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as gemcitabine and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…NCT00792701·Fort Smith, Arkansas and 146 others

CompletedCryotherapy in Treating Patients With Primary Lung Cancer or Lung Metastases That Cannot Be Removed By SurgeryRATIONALE: Cryotherapy kills tumor cells by freezing them. This may be an effective treatment for primary lung cancer or lung metastases that cannot be removed by surgery.NCT00303901·Detroit, Michigan

CompletedPhase III of RRM1 & ERCC1 Directed Customized Chemotherapy for the Treatment of Patients With NSCLCThis is a clinical research study to evaluate if chemotherapy in the experimental arm (E) results in a better outcome compared to patients in the standard of care arm (C).NCT00499109·Lakeland, Florida and 8 others

CompletedHigh-Dose or Standard-Dose Radiation Therapy and Chemotherapy With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by SurgeryRATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells.NCT00533949·Birmingham, Alabama and 212 others

TerminatedA Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2A Study of XMT-2056 in advanced/recurrent solid tumors that express HER2.NCT05514717·Los Angeles, California and 13 others

CompletedPhase 1/1b Study of MGCD516 in Patients With Advanced CancerMGCD516 is a receptor tyrosine kinase (RTK) inhibitor shown in preclinical models to inhibit a closely related spectrum of RTKs including MET, AXL, MER, and members of the VEGFR…NCT02219711·Birmingham, Alabama and 42 others

CompletedA Study of BGB324 (Bemcentinib) in Combination With Erlotinib in Patients With Non-Small Cell Lung CancerA Phase 1/2 multi-center open-label study of BGB324 (bemcentinib) as a single agent (Run-in Cohort) and in combination with erlotinib (Arms A, B, and C) in participants with Stage…NCT02424617·La Jolla, California and 9 others

CompletedA Study Comparing Alectinib With Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer ParticipantsThis randomized, active controlled, multicenter phase III open-label study is designed to evaluate the efficacy and safety of alectinib compared with crizotinib treatment in…NCT02075840·Northridge, California and 96 others

TerminatedAn Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung CancerThe purpose of this study is to determine whether Nivolumab, in combination with other therapies, is effective in patients with advanced Non-Small Cell lung cancerNCT02750514·Duarte, California and 49 others

Active not recruitingBasket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor an NTRK1/2/3, ROS1, or ALK…NCT02568267·Phoenix, Arizona and 119 others

Active not recruitingA Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)The primary objective of Parts 1 and 2 of this study is to evaluate the safety, tolerability, and to determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D)…NCT05094336·Duarte, California and 74 others

Active not recruitingMaintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung CancerThis randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small…NCT03137771·Birmingham, Alabama and 300 others

RecruitingFirst-in-human Study of Interferon-y PET Imaging to Assess Response to ImmunotherapyThe goal of this clinical trial is to investigate the use of \[89Zr\]Zr-DFO-emapalumab as an IFN-γ PET imaging agent to detect lesions and response to therapy among…NCT06439914·Detroit, Michigan

TerminatedKEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLCThis is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with…NCT04265534·Birmingham, Alabama and 101 others

TerminatedIMM60 and Pembrolizumab in Melanoma and NSCLCThe goal of this clinical trial is to learn about IMM60 with or without pembrolizumab in participants with advanced melanoma or non-small cell lung cancer.NCT05709821·Los Angeles, California and 13 others

CompletedCAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLCThe objective of this study is to assess safety and efficacy of CAB-AXL-ADC in NSCLCNCT04681131·Duarte, California and 59 others

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