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Clareo Health | Lung Cancer Clinical Trials in Detroit | 433 Studies

Clinical Trials Lung CancerDetroit

Lung Cancer Clinical Trials in Detroit

Find 433 clinical trials for lung cancer near Detroit, Michigan. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Detroit

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 201-220 of 433 trials

CompletedA Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"This multicenter, open-label, randomized study will evaluate the efficacy and safety of Atezolizumab compared with docetaxel in participants with advanced or metastatic non-small…NCT01903993·Tucson, Arizona and 64 others

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Data from ClinicalTrials.govTerms

CompletedPhase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLCThis is an open-label, multicenter, 2-arm study to evaluate the safety and preliminary efficacy of the addition of a vaccine therapy to 1 or 2 checkpoint inhibitors for NSCLC.NCT03164772·Gilbert, Arizona and 4 others

TerminatedA Safety and Efficacy Study of INC280 Alone, and in Combination With Erlotinib, Compared to Chemotherapy, in Advanced/Metastatic Non-small Cell Lung Cancer Patients With EGFR Mutation and cMET AmplificationThe purpose of this study was to determine the maximum tolerated dose (MTD) or recommended phase II dose (RP2D) of INC280 in combination with erlotinib in the Phase Ib of this…NCT02468661·Los Angeles, California and 31 others

Active not recruitingStudy of Furmonertinib in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Activating, Including Uncommon, Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) MutationsThis is a Phase 1b, open-label, multi-center, dose-escalation and dose expansion study designed to evaluate the safety, pharmacokinetics (PK), and preliminary antitumor activity…NCT05364073·Prescott, Arizona and 41 others

CompletedA Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)This is a trial in adult participants with unresectable, locally advanced, Stage III non-small cell lung cancer (NSCLC) treated with pembrolizumab in combination with platinum…NCT03631784·Santa Rosa, California and 55 others

Active not recruitingA Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor…NCT04487080·Goodyear, Arizona and 268 others

CompletedStereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain MetastasesRATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue.NCT00377156·Phoenix, Arizona and 63 others

CompletedA Phase 1b Study of Atezolizumab in Combination With Erlotinib or Alectinib in Participants With Non-Small Cell Lung Cancer (NSCLC)This open-label, multicenter study will assess the safety, tolerability, and pharmacokinetics of intravenous (IV) dosing of atezolizumab in combination with oral erlotinib or…NCT02013219·Orange, California and 16 others

CompletedM7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)The purpose of the study is to evaluate the efficacy and safety of bintrafusp alfa (M7824) compared with pembrolizumab in participants with advanced NSCLC with high PD-L1-tumor…NCT03631706·Huntsville, Alabama and 118 others

CompletedStudy Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Placebo Plus Carboplatin and Paclitaxel in Previously Untreated Advanced or Metastatic Squamous Non-Small Cell Lung CancerThe purpose of this study is to evaluate the safety and efficacy of the addition of veliparib plus carboplatin and paclitaxel versus the addition of placebo plus carboplatin and…NCT02106546·Jonesboro, Arkansas and 224 others

CompletedStudy of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid TumorsThe purpose of this study is to find out if panobinostat taken with cisplatin and pemetrexed can be used safely without increasing side effects and that the combination will have…NCT01336842·Sacramento, California and 1 other

TerminatedSafety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung CancerThe goal of this clinical trial is to compare the safety and efficacy (how well the drug works) of acasunlimab (also known as GEN1046) when it is used alone (monotherapy) versus…NCT05117242·Santa Rosa, California and 39 others

Active not recruitingA Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With SurgeryThis study is researching an experimental drug called fianlimab (also called REGN3767) with two other medications called cemiplimab and platinum-doublet chemotherapy, individually…NCT06161441·Clermont, Florida and 122 others

Active not recruitingErlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung CancerThis randomized phase II trial studies how well giving erlotinib hydrochloride and cabozantinib-s-malate alone or in combination works as second or third line therapy in treating…NCT01708954·Scottsdale, Arizona and 355 others

CompletedNon-small Cell Lung Cancer RegistryThis trial will evaluate two separate groups of patients with stage IIIB/IV non-small cell lung cancer.NCT00099541·Birmingham, Alabama and 100 others

RecruitingStudy of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung CancerThe main purpose of this study is to assess if olomorasib in combination with pembrolizumab is more effective than the pembrolizumab and placebo combination in part A in…NCT06890598·Huntsville, Alabama and 367 others

TerminatedCaptopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without ChemotherapyRATIONALE: Captopril is a drug that may be able to decrease side effects caused by radiation therapy, and may improve the quality of life of patients with non-small cell lung…NCT00077064·Birmingham, Alabama and 86 others

Active not recruitingTesting the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung CancerThis phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell…NCT04092283·Anchorage, Alaska and 829 others

RecruitingA Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsPhase 1 dose escalation will determine the first cycle dose-limiting toxicities (DLTs), the maximum tolerated dose (MTD), the biologically effective dose and recommended Phase 2…NCT03093116·Duarte, California and 164 others

Active not recruitingStudy of AB598 Monotherapy and Combination Therapy in Participants With Advanced CancersThe primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.NCT05891171·Phoenix, Arizona and 13 others

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