Leukemia Clinical Trials

Showing 4021-4040 of 10,987 trials

Impact of Interventions on Admission SOFA Score on Clinical Outcomes of Critically Ill Patients

NCT05790915

Introduction: The SOFA score (Sequential Organ Function Assessment) and its derived measures, such as the Delta SOFA, are used worldwide to determine the severity and prognosis of critically ill patients. Objectives: The primary objective of this study was to assess the impact of standardized interventions on the six organ dysfunctions of SOFA score on outcomes of critically ill patients through the 48-hour delta SOFA with evaluation of the effectiveness of the interventions performed. Result will be correlated with the 28-day mortality. The secondary outcome measures comprised the evaluation of standardized interventions on ICU and hospital length of stay; vasopressor-free and ventilator-free days within the 28 days following ICU admission, through the effectiveness of interventions performed Uni and multivariate statistical analysis will be used to determine organ failures associated to outcome.

Critically Ill Patients

Hospital Sao Domingos849 participantsStarted Aug 2023

São Luís, Maranhão, Brazil

COMPLETEDPhase 2

An Exploratory Study of the Effects of Nivolumab Combined With Ipilimumab in Patients With Treatment-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)

NCT03001882

The purpose of this study is to explore the possible links between participant characteristics and their cancer, with how effective the combination of nivolumab with ipilimumab is, in participants with Stage IV or recurrent Non-Small Cell Lung Cancer (NSCLC).

Non-Small Cell Lung Cancer

Bristol-Myers Squibb230 participantsStarted Mar 2017

Springdale, Arkansas, United States • New Haven, Connecticut, United States • Jacksonville, Florida, United States +32 more locations

Impact of Interventions on Admission SOFA Score on Clinical Outcomes of Critically Ill Patients

An Exploratory Study of the Effects of Nivolumab Combined With Ipilimumab in Patients With Treatment-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)

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