Leukemia Clinical Trials

Showing 3841-3860 of 6,732 trials

Concurrent Chemoradiotherapy Combination With Anlotinib for Limited-stage Small Cell Lung Cancer

NCT04882033

The purpose of this study is to evaluate the tolerability and toxicity of different dose of anlotinib combination with concurrent chemoradiotherapy in the treatment of limited-stage SCLC patients.

Small Cell Lung Cancer Limited Stage

Tianjin Medical University Cancer Institute and Hospital9 participantsStarted May 2021

Tianjin, Tianjin Municipality, China

COMPLETEDPhase 1

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

NCT02129582

This phase I trial studies the side effects and best dose of targeted marrow irradiation when given with fludarabine phosphate and busulfan before donor progenitor cell transplant in treating patients with hematologic malignancies. Targeted marrow irradiation is a type of specialized radiation therapy that delivers a high dose of radiation directly to the cancer cells, which may kill more cancer cells and cause less damage to normal cells. Giving targeted marrow irradiation and chemotherapy drugs, such as fludarabine phosphate and busulfan, before a donor progenitor cell transplant may help stop the growth of cancer cells. It may also stop the patient's immune system from rejecting the donor's progenitor cells. When the healthy progenitor cells from a donor are infused into the patient they may help the patient's bone marrow make progenitor cells, red blood cells, white blood cells, and platelets.

Acute Myeloid LeukemiaHematologic MalignanciesAcute Lymphocytic Leukemia+8 more

Case Comprehensive Cancer Center14 participantsStarted Nov 2014

Cleveland, Ohio, United States

Concurrent Chemoradiotherapy Combination With Anlotinib for Limited-stage Small Cell Lung Cancer

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

Related Searches

Neoadjuvant Toripalimab Plus Platinum-based Doublet for Stage III Non-small Cell Lung Cancer

Bevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

White Matter Hyperintensities Subtypes in Cerebral Small Vessel Disease : 7 Tesla Ultra-high Resolution Imaging MRI

Phase II Study of Radiation Therapy and Vismodegib for Advanced Head/Neck Basal Cell Carcinoma

Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness.

The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation

Blinatumomab in High-risk B-cell Precursor Acute Lymphoblastic Leukemia

Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

New Validated Recipes for Double-blind Placebo-controlled Low Dose Food Challenges

Efficacy and Safety of Prophylactic Cranial Irradiation Versus MRI Surveillance in Patients With Limited-stage Small Cell Lung Cancer Who Achieved Remission After First-line Chemoradiotherapy

Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers

How Anxiety in Pregnant Hospitalized Women Change wIth Internet Use

Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients

Assessment of Endothelial and Haemostatic Changes During Severe SARS-CoV-2 Infection

Small Fiber Assessment by Cutaneous Silent Period

Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.

Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors