Leukemia Clinical Trials

Showing 3181-3200 of 10,987 trials

Study of the Immunological Infiltrate and Immunometabolic Immunometabolic Profile of Patients with Acute Leukaemia

NCT06814444

LThe main aim of this project is to provide an immunophenotypic and immunometabolic characterisation of patients with Acute Leukaemia, before and after therapy, and to understand how changes in the immune system impact the response to therapy. Specifically: 1. The association between the molecular and metabolic characteristics of leukaemic cells and those of the surrounding immune system will be assessed, in order to identify immune-modulatory metabolic mechanisms activated by malignant cells. 2. The association between immunometabolic signatures and response to therapies will be assessed. 3. The role of EVs as a vehicle for metabolic units capable of regulating the metabolism of immune system cells will be explored.

Acute Leukemia

IRCCS Azienda Ospedaliero-Universitaria di Bologna170 participantsStarted Nov 2023

Bologna, Bologna, Italy

RECRUITINGNA

Effects of Ventilator Hyperinflation Versus Vibrocompression in Mechanically Ventilated Patients

NCT06791798

The aim of the current study is to compare the effects of ventilator hyperinflation and vibrocompression on lung compliance in mechanically ventilated patients.

Mechanically Ventilated PatientsLung ComplianceAirway Clearance Impairment

Cairo University81 participantsStarted Feb 2025

Cairo, Egypt

Study of the Immunological Infiltrate and Immunometabolic Immunometabolic Profile of Patients with Acute Leukaemia

Effects of Ventilator Hyperinflation Versus Vibrocompression in Mechanically Ventilated Patients

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