Leukemia Clinical Trials

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AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

NCT04770012

Cardiac allograft vasculopathy is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. The research team is investigating whether early antiplatelet therapy post heart transplant can prevent the development of CAV. This study will determine the feasibility of a large multicenter randomized placebo-controlled trial to answer this question.

Cardiac Allograft VasculopathyHeart Transplant

Ottawa Heart Institute Research Corporation135 participantsStarted Jun 2021

Vancouver, British Columbia, Canada • Ottawa, Ontario, Canada • Toronto, Ontario, Canada

TERMINATEDPhase 2

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

NCT04383210

This study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene fusion.

Locally Advanced Solid TumorMetastatic Solid TumorPancreatic Cancer+14 more

Elevation Oncology54 participantsStarted Sep 2020

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Fountain Valley, California, United States +39 more locations

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

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