Leukemia Clinical Trials

Showing 2381-2400 of 10,987 trials

Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery

NCT04025840

Pancreatic cancer remains a devastating disease with an average 5-year survival rate of about 3-5%. Previous retrospective studies showed that perioperative epidural block and/or dexamethasone are associated with improved outcome after cancer surgery. This randomized trial aims to investigate the effect of perioperative epidural block and/or dexamethasone on long-term survival in patients following pancreatic cancer surgery.

Pancreatic CancerSurgeryEpidural Block+2 more

Peking University First Hospital260 participantsStarted Sep 2019

Beijing, Beijing Municipality, China

TERMINATEDPhase 1/2

MGC018 With or Without MGA012 in Advanced Solid Tumors

NCT03729596

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics (PK) pharmacodynamics and preliminary antitumor activity of vobramitamab duocarmazine (MGC018) in patients with advanced solid tumors. Patients with solid tumors will be enrolled in the Dose Escalation Phase; Cohort Expansion will include metastatic castrate-resistant prostate cancer (mCRPC), non-small cell lung cancer (NSCLC), triple-negative breast cancer (TNBC), squamous cell carcinoma of the head and neck (SCCHN), and melanoma. Patients who do not experience unacceptable toxicity or meet criteria for permanent discontinuation may undergo additional cycles for up to two years. Patients in Cohort Expansion will be followed for survival every 3 months for 2 years following last dose.

Squamous Cell Carcinoma of Head and NeckTriple Negative Breast CancerMelanoma+3 more

MacroGenics143 participantsStarted Nov 2018

Santa Monica, California, United States • Washington D.C., District of Columbia, United States • Baltimore, Maryland, United States +18 more locations

Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery

MGC018 With or Without MGA012 in Advanced Solid Tumors

Related Searches

64Cu-LLP2A for Imaging Hematologic Malignancies

Neoadjuvant and Adjuvant Toripalimab and Cetuximab in Patients With Recurrent, Resectable Squamous Cell Carcinoma of Head and Neck: a Prospective, Single-arm,Phase II Study

Impact of Supplemental Fiber on Gut and Vascular Health Related in Obesity Phenotypes

Nylon Versus Chromic Gut Sutures for Minor Hand Surgery

Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs

Camu-Camu Prebiotic and Immune Checkpoint Inhibition in Patients With Non-small Cell Lung Cancer and Melanoma

HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

Aging and Task-specific Training to Reduce Falls

Effect of G-CSF on MDSC and Cancer Stem-cells Interactions in Non-small Cell Lung Cancers (CIRCUIT)

Impact of Optical Genome Mapping in Acute Myeloblastic Leukemia

Lifestyle Intervention on Patients With Overweight or Obesity

The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia

Bevacizumab Combined With Cisplatin Versus Cisplatin Monotherapy in Malignant Serous Effusions

Steady Stride Fall Prevention Protocol vs Standard of Care

STI Testing to Enhance PrEP Use in Pregnancy

Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome