64Cu-LLP2A for Imaging Hematologic Malignancies

Inclusion Criteria

• •Adult 18 years of age or older
• •Able to give informed consent.
• •Able to comprehend and willing to follow instructions for study procedures as called for by the protocol
• •Capable of lying still and supine within the PET/CT scanner for up to 75 minutes.
• •No illicit drug use or other inhaled drug use (including pharmacologic agents and illicit drugs) within the past year per self-reporting mechanisms.
• •No history of claustrophobia or other condition that has previously or would interfere with completion of protocol specified imaging sessions.
• •Not currently pregnant or nursing: Subject must be surgically sterile (has had a documented bilateral oophorectomy and/or documented hysterectomy), post-menopausal (cessation of menses for more than 1 year), non-lactating, or of childbearing potential for whom a urine pregnancy test (with the test performed within the 24 hour period immediately prior to administration of 64Cu-LLP2A) is negative.
• •Clinical or pathologically defined MM or lymphoma including both newly diagnosed, relapsed or refractory disease:
• •* Multiple Myeloma defined in accordance with the International Myeloma Working Group criteria
• •* Low-grade lymphoma, including the following subtypes: follicular lymphoma, marginal zone lymphoma, lymphoplasmacytic lymphoma, small lymphocytic lymphoma/chronic lymphocytic leukemia
• +5 more criteria