Leukemia Clinical Trials in Philadelphia

Showing 561-580 of 1,308 trials

MIRACLE of LIFE Study

NCT06074601

The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1. Can cell-free RNA-based biomarkers predict which pregnant people are at greatest risk of developing adverse pregnancy outcomes (e.g., preterm birth, preeclampsia)? 2. What is the performance of such biomarkers when predicting an adverse pregnancy outcome (e.g., sensitivity, specificity, PPV, NPV, TPR)?

Preterm LaborPreterm BirthPreterm Birth Complication+7 more

Mirvie10,000 participantsStarted Aug 2021

San Diego, California, United States • Orlando, Florida, United States • New Orleans, Louisiana, United States +7 more locations

COMPLETEDPhase 2< 1 mile

Trametinib in Treating Patients With Epithelioid Hemangioendothelioma That is Metastatic, Locally Advanced, or Cannot Be Removed by Surgery

NCT03148275

This phase II trial studies how well trametinib works in treating patients with epithelioid hemangioendothelioma that has spread to other places in the body (metastatic), nearby tissue or lymph nodes (locally advanced), or cannot be removed by surgery (unresectable). Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Locally Advanced Epithelioid HemangioendotheliomaMetastatic Epithelioid HemangioendotheliomaUnresectable Epithelioid Hemangioendothelioma

National Cancer Institute (NCI)44 participantsStarted Jun 2017

Phoenix, Arizona, United States • Scottsdale, Arizona, United States • Palo Alto, California, United States +33 more locations

MIRACLE of LIFE Study

Trametinib in Treating Patients With Epithelioid Hemangioendothelioma That is Metastatic, Locally Advanced, or Cannot Be Removed by Surgery

Leukemia Trials in Other Cities

A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007

Rollover Study for Subjects Who Have Participated in an Astellas Sponsored ASP2215 Trial

Pediatric Cardiac Output Monitoring Observational Study

Functional Lung Imaging With DECT and 4DCT

A Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations

Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers

A Study of ZN-c3 in Patients With Ovarian Cancer

A Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS)

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

A Study Evaluating the Safety and Efficacy of Brexucabtagene Autoleucel (KTE-X19) in Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ZUMA-3)

A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors

First in Human Study of M1069 in Advanced Solid Tumors

Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas

Stratification of Risks of Conversion of Radiologically Isolated Syndromes (RIS) by Identifying Biomarkers in Serum and Cerebrospinal Fluid.

Other Conditions in Philadelphia