Leukemia Clinical Trials in Pennsylvania

Showing 401-420 of 808 trials

Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML

NCT04002115

The Investigators would like to study the incidence of complete remission (CR) at day +30 after Clofarabine followed by haploidentical transplant. The conditioning regimen used is Fludarabine, Busulfan (2 doses) or cyclophosphamide (2 doses) and Total Body Irradiation (TBI) with post transplant cyclophosphamide for patients with Acute Myeloid Leukemia (AML) who are not in remission prior to considering allogeneic transplant with haploidentical donors.

Acute Myeloid Leukemia

Milton S. Hershey Medical Center2 participantsStarted Jun 2020

Hershey, Pennsylvania, United States

TERMINATEDPHASE195 miles

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

NCT01186328

An experimental drug called EZN-3042 targets survivin, a protein expressed in leukemia cells at relapse that promotes the leukemia cells to grow. The main goal of this phase I study is to find out the dose of EZN-3042 that can be safely given without serious side effects both alone and in combination with standard chemotherapy drugs during re-induction.

Lymphoblastic Leukemia, AcuteLymphoblastic Leukemia, Acute, ChildhoodLeukemia, Lymphoblastic, Acute, T Cell+1 more

Therapeutic Advances in Childhood Leukemia Consortium6 participantsStarted Aug 2010

Los Angeles, California, United States • Baltimore, Maryland, United States • Minneapolis, Minnesota, United States +4 more locations

Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Leukemia Trials in Other Cities

BIO 300 Non-Small Cell Lung Cancer Study

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer

Studying Tissue and Blood Samples From Patients With Acute Myeloid Leukemia

Diagnostic Study of Patients With Acute Lymphoblastic Leukemia or Acute Promyelocytic Leukemia

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -

A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia

Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population

Study of Pembrolizumab Given With Ipilimumab or Placebo in Participants With Untreated Metastatic Non-Small Cell Lung Cancer (NSCLC) (MK-3475-598/KEYNOTE-598)

An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

A Phase 1 Study to Evaluate FN-1501 Monotherapy in Patients With Advanced Solid Tumors and R/R AML

Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia

A Dose Escalation and Confirmation Study of PT-112 in Advanced Solid Tumors in Combination With Avelumab

Survival Prolongation by Rationale Innovative Genomics

Other Conditions in Pennsylvania