Kidney Disease Clinical Trials

Showing 1481-1500 of 1,850 trials

Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients

NCT02683291

There is no consensus on the best immunosuppressive regimen in elderly people. The aim of this study will be to evaluate the efficacy of sirolimus associated with tacrolimus in elderly kidney transplant recipients. The investigators will conduct a single-center prospective randomized study comparing the combination of tacrolimus with sirolimus at reduced dose rate (tacrolimus + sirolimus group) against tacrolimus with mycophenolate (tacrolimus + mycophenolate group). The investigators will include all kidney transplant patients over 60 years of age. The investigators will evaluate estimated glomerular filtration rate and incidence of cytomegalovirus in 12 month follow-up.

Associação Médico Espírita de Botucatu48 participantsStarted Jan 2014

COMPLETEDPhase 1

A Multiple-Dose Study of Oral Oseltamivir in Participants on Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD)

NCT02617784

This study is designed to assess the pharmacokinetics (PK) and safety of oseltamivir and its metabolite oseltamivir carboxylate in participants undergoing routine HD and CAPD for end-stage renal disease (ESRD). Participants will receive 6.5 and 6 weeks of the marketed oral oseltamivir suspension dosed according to the HD or CAPD schedule, respectively.

End Stage Renal Disease

Hoffmann-La Roche24 participantsStarted Oct 2001

Christchurch, New Zealand

UNKNOWNPhase 1/2

A Dose Escalation Study of VS-505 in End Stage Renal Disease Patients Undergoing Hemodialysis

NCT02469467

The purpose is to evaluate the tolerability, safety and efficacy of VS-505 when given with meal for 8 weeks to hemodialysis patients with hyperphosphatemia

End Stage Renal DiseaseHyperphosphatemia

KDL Inc.30 participantsStarted Jun 2015

Perth, Western Australia, Australia

Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients

A Multiple-Dose Study of Oral Oseltamivir in Participants on Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD)

A Dose Escalation Study of VS-505 in End Stage Renal Disease Patients Undergoing Hemodialysis

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