Kidney Disease Clinical Trials

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Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease

NCT03865407

Aim 1. To determine the effect of Allopurinol treatment on renal function (glomerular filtration rate, GFR) in pediatric chronic kidney disease (CKD) patients with high uric acid levels (hyperuricemia). Aim 2. Establish whether Allopurinol treatment reduces Nlrp3 inflammasome and renal injury biomarkers.

HyperuricemiaChronic Kidney Diseases

Virginia Commonwealth University17 participantsStarted Mar 2019

Richmond, Virginia, United States

TERMINATEDPHASE4

Conversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease Stage 5

NCT00452478

The main aim of this research study is to see if giving Fosrenol®, a chewable tablet, to patients on haemodialysis works as well as other treatments currently used to lower blood phosphorus levels.

Kidney Diseases

Shire68 participantsStarted May 2007

Feldkirch Tisis, Austria • Linz, Austria • Genk, Belgium +11 more locations

Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease

Conversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease Stage 5

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