Hypertension Clinical Trials in Chicago

Showing 21-40 of 221 trials

FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

NCT07332741

The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control. The 24-week trial includes a 12-week FIM+DASH intervention followed by a 12-week maintenance period and leverages existing partnerships with community-based organizations for home food delivery and culinary skill-skill building. The main questions it aims to answer are: (1) What is the effect of FIM+DASH vs. usual care control on blood pressure? (2) What is the effect of FIM+DASH vs. usual care control on DASH diet adherence (diet quality), body weight, and waist circumference? (3) How to identify factors associated with the sustainability and scalability of FIM+DASH in real-world settings?

HypertensionHypertension (HTN)Obesity & Overweight

University of Illinois at Chicago150 participantsStarted Mar 2026

Chicago, Illinois, United States • Chicago, Illinois, United States • Chicago, Illinois, United States +1 more locations

RECRUITINGPhase 42.2 miles

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

NCT06468202

The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy (HDP), and that there are multiple factors associated with adherence with aspirin therapy that will be important to identify to enable optimal implementation of study findings and population-level benefits.

Hypertensive Disorders of PregnancyPreeclampsiaGestational Hypertension

Ohio State University10,742 participantsStarted Oct 2024

Birmingham, Alabama, United States • Los Angeles, California, United States • San Francisco, California, United States +13 more locations

FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

Hypertension Trials in Other Cities

A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Novartis - Closing the Gap in Cardiovascular Risk: Engage, Empower, Evaluate

Community Intervention to Reduce CardiovascuLar Disease in Chicago

The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia

Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

Selexipag (ACT-293987) in Pulmonary Arterial Hypertension

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction

A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis

Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)

Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

Other Conditions in Chicago