Heart Disease Clinical Trials in Philadelphia

Showing 161-180 of 468 trials

Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound

NCT03245255

This study will use contrast echocardiography to assess the accuracy of a new non-invasive imaging method for subharmonic aided pressure estimation (SHAPE) compared to simultaneously acquired intra-cardiac pressures measured invasively during cardiac catheterization. This study is designed to verify that contrast echocardiography using the SHAPE method, already proven in a canine model and tested in a human pilot study can be used as a surrogate for cardiac catheterization with sufficient accuracy to allow clinical applicability in humans.

Cardiac CatheterizationBlood PressureHeart Ventricles+2 more

Thomas Jefferson University80 participantsStarted Dec 2017

Philadelphia, Pennsylvania, United States

TERMINATEDPhase 1/2< 1 mile

Use of Oxandrolone to Promote Growth in Infants With HLHS

NCT04090697

The primary aim of this study is to determine if clinically relevant doses of buccally administered oxandrolone are safe and tolerable in neonates with hypoplastic left heart syndrome (HLHS) or other single right ventricular anomalies who have undergone a Norwood procedure. The secondary aim is to evaluate the efficacy of buccally administered oxandrolone in improving objective indices of growth and nutrition in neonates who have undergone a Norwood procedure.

Hypoplastic Left HeartCongenital Heart Disease

Carelon Research34 participantsStarted Dec 2019

Atlanta, Georgia, United States • Boston, Massachusetts, United States • Ann Arbor, Michigan, United States +7 more locations

Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound

Use of Oxandrolone to Promote Growth in Infants With HLHS

Heart Disease Trials in Other Cities

Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)

Default Bulk Ordering and Text Messaging to Enhance Outreach for Lipid Screening (Missing Lipids)

A Study to Evaluate Lung Ultrasound as a Method to Measure Changes in Extravascular Lung Water Induced by Positional Changes (LUPE)

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

Multiple Cardiac Sensors for the Management of Heart Failure

The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota

Safe Surveillance of PCI Under Mechanical Circulatory Support With the Saranas Early Bird Bleed Monitoring System

Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™

A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon

ANTHEM-HFrEF Pivotal Study

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

ELUCIDATE FFRct Study

A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)

Rivet PVS Therapy in Group 2 PH-HFpEF

Cardionomic STOP-ADHF Study

Other Conditions in Philadelphia