Heart Disease Clinical Trials in Massachusetts

Showing 361-380 of 532 trials

Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid

NCT01159054

Patients with kidney failure on hemodialysis have an extremely high rate of cardiovascular disease including atherosclerotic cardiovascular disease. This, at least in part, is due to the chronic inflammatory status usually seen in these patients. Here we try to see if treatment with extended release nicotinic acid (Niaspan) can reduce their overall inflammatory burden (in general) and the atherosclerotic plaque inflammation (in particular).

DialysisCardiovascular DiseaseAtherosclerosis+1 more

Brigham and Women's Hospital22 participantsStarted Jul 2010

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Somerville, Massachusetts, United States

COMPLETEDPhase 326 miles

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

NCT00116428

This trial compares the safety and effectiveness of catheter ablation for PAF with antiarrhythmic drug therapy. The investigational catheter being studied is the NAVISTAR® THERMOCOOL® irrigated-tip catheter. At the time of this study, the NAVISTAR® THERMOCOOL® catheter was FDA-approved for commercial distribution in the U.S. for treating patients with Type I atrial flutter and drug refractory monomorphic ventricular tachycardia post myocardial infarction. The catheter was approved for use in Europe for endocardial ablation for treating cardiac arrhythmias.

Heart DiseasesArrhythmiaAtrial Fibrillation

Biosense Webster, Inc.167 participantsStarted Oct 2004

Greenbrae, California, United States • Orlando, Florida, United States • Maywood, Illinois, United States +14 more locations

Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

Heart Disease Trials in Other Cities

An Observational Study of Cholesterol in Coronary Arteries

Significance of Antibodies to Heparin/Platelet Factor 4 Complex in Vein Graft Patency and Potential Role of Argatroban for Prevention of Vein Graft Occlusion

Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

Educational and Supportive Interventions to Prevent Cardiopulmonary Rehospitalization

Physical Health in Midlife: Influences of Adversity and Relationships Over Time

Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure

Glycemic Index - Variability Among Individuals

Impact of Gum Infection on Heart Disease

Role of Plavix in Hemorrhagic and Ischemic Complications of Catheterization.

Processing Responses of Grains (PRO-Grains) Study

Peri-operative Assessment of Coagulopathy in Neonates and Infants Undergoing Cardiac Surgery

Thiamine as an Adjunctive Therapy in Cardiac Surgery

Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study

Tea's Effect on Atherosclerosis Pilot Study (TEA Study)

Assessment of Optimal Egg Intake in a Healthy Population

A Prospective, Multi-Center, Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter in Facilitating Crossing Chronic Total Occlusion (CTO) Coronary Lesions

Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients

Other Conditions in Massachusetts