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Clareo Health | Heart Disease Clinical Trials in Massachusetts | 28 Studies

Clinical Trials Heart DiseaseMassachusetts

Heart Disease Clinical Trials in Massachusetts

Find 28 clinical trials for heart disease near Massachusetts. Connect with research centers in your area.

All Heart Disease trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 28 trials

WithdrawnDose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial HypertensionThe purpose of this study is to determine the safety and maximum tolerated dose of inhaled NX1011 for the treatment of pulmonary arterial hypertension (PAH).NCT00323024·Phoenix, Arizona and 5 others TerminatedThe Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension StudyThe purpose of this study is to find out if spironolactone added to ambrisentan for Pulmonary Arterial Hypertension (PAH) will increase exercise capacity.NCT02253394·Boston, Massachusetts Enrolling by invitationEffect of PEEP on Cardiac FunctionThe purpose of this single-center, prospective study is to evaluate the physiologic effect of changes in PEEP on biventricular mechanics and RV-pulmonary arterial (RV-PA) coupling…NCT07531602·Boston, Massachusetts RecruitingTrial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureThe purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of…NCT06526195·Phoenix, Arizona and 67 others

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Data from ClinicalTrials.govTerms

TerminatedPulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan)This pilot study will assess the impact of sacubitril/valsartan (trade name Entresto) on the elevated pulmonary artery pressures in patients with heart failure with reduced…NCT02788656·Boston, Massachusetts

CompletedStudy to Investigate CSL112 in Subjects With Acute Coronary SyndromeThis is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major…NCT03473223·Alexander City, Alabama and 902 others

CompletedRandomized Endo-Vein Graft ProspectiveCoronary artery bypass grafting (CABG) is the most common major surgical procedure in the United States with over 300,000 cases performed each year.NCT01850082·Tucson, Arizona and 15 others

CompletedImproving Quality by Maintaining Accurate Problems in the EHRThe overall goal of the IQ-MAPLE project is to improve the quality of care provided to patients with several heart, lung and blood conditions by facilitating more accurate and…NCT02596087·Boston, Massachusetts and 3 others

CompletedPrevention of Autogenous Vein Graft Failure in Coronary Artery Bypass ProceduresThe purpose of this study is to determine the efficacy of graft pretreatment with CGT003 (E2F Duplex Decoy), as compared to placebo, on the incidence of patients experiencing vein…NCT00042081·Birmingham, Alabama and 153 others

CompletedPrevention of Serious Adverse Events Following AngiographyThe purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine…NCT01467466·Tucson, Arizona and 53 others

RecruitingPharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults…NCT04278404·Phoenix, Arizona and 51 others

RecruitingCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)This is a two-part, phase 2b and phase 3 combined prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study.NCT05485961·Decatur, Alabama and 565 others

TerminatedRisk Factors for Coronary Artery Calcification and Left Ventricular Hypertrophy in Hemodialysis PatientsIndividuals with kidney disease are at a higher risk for heart and vascular diseases, including heart attacks and strokes, than those with normal kidney function.NCT01427374·Indianapolis, Indiana and 3 others

CompletedA Collaborative Care Program to Improve Depression Treatment in Cardiac PatientsDepression in cardiac patients is common, persistent, and deadly.NCT00847132·Boston, Massachusetts

CompletedNHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR TrialBackground: Replacing a valve in the heart can save many people's lives. The procedure is called transcatheter aortic valve replacement (TAVR).NCT05666713·San Francisco, California and 9 others

RecruitingPulmonary Artery Catheter in Cardiogenic Shock TrialThe primary objective of the PACCS trial is to assess if early invasive hemodynamic assessment and ongoing management with a PAC in patients with cardiogenic shock due to acutely…NCT05485376·Boston, Massachusetts

Active not recruitingImproving Cardiac Rehabilitation Exercise Using Target Heart Rate TrialThe goal of this clinical trial is to compare two types of exercise prescriptions in cardiac rehabilitation eligible older adults (60 years or older) with heart disease.NCT05925634·Springfield, Massachusetts and 1 other

UnknownGet Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older AdultsA multicenter prospective randomized clinical trial testing the hypothesis that a patient-centered actigraphy intervention will result in increased physical activity for frail…NCT02635477·Atlanta, Georgia and 15 others

Enrolling by invitationPulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)This early feasibility study is intended to characterize the impact of pulmonary artery denervation on the quality of life in Heart Failure Patients with Group 2 Pulmonary…NCT06052072·Chicago, Illinois and 7 others

RecruitingANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)The primary objective of this protocol is to develop a comprehensive, multicenter international prospective registry to capture long-term clinical outcomes for adult patients…NCT07559903·Phoenix, Arizona and 18 others

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