Heart Disease Clinical Trials in Detroit

Showing 101-120 of 263 trials

Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations

NCT01262625

This randomized, controlled, diagnostic, multicenter trial will compare two diagnostic imaging pathways--coronary computed tomography angiography (CCTA) and single photon emission tomography (SPECT) myocardial perfusion imaging (MPI)--to determine the incidence of major adverse coronary events (MACE), defined as myocardial infarction (MI) or cardiac-related death, and cross-over to revascularization. CCTA may be used to direct patients with symptoms of stable angina or angina equivalent to optimal medical therapy (OMT). The use of CCTA as a diagnostic tool for angina symptoms will be associated with no increase in MACE or revascularization, decreased cost, reduced risks (e.g., less radiation exposure), additional insights into alternate explanations of chest pain, and increased cost-effectiveness in comparison with use of SPECT MPI/invasive coronary angiography (ICA).

Chest PainStable Angina Pectoris, CCS Class I to IIIAngina Equivalent+1 more

American College of Radiology1,050 participantsStarted May 2011

Decatur, Georgia, United States • Detroit, Michigan, United States • Salem, Virginia, United States

UNKNOWNNA< 1 mile

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

NCT03108456

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).

Coronary Artery DiseaseIschemic Heart DiseaseNon ST Segment Elevation Myocardial Infarction

Abbott Medical Devices2,005 participantsStarted Mar 2017

Birmingham, Alabama, United States • Chandler, Arizona, United States • Phoenix, Arizona, United States +101 more locations

Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Heart Disease Trials in Other Cities

Access Natriuretic Peptide Assay(s) Pivotal - Emergency Department Subject Enrollment and Specimen Collection

Novel Cardiac Rehabilitation in Patients Heart Failure and Preserved Ejection Fraction

RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

Identifying and Facilitating Ventricular Recovery on Mechanical Support

Ventricular Assist Device (VAD) Infection Prevention Survey

Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure

Enhanced Physical Activity Support in Congenital Heart Disease Clinical Care

A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure

Vascular Inflammation in Psoriasis - Apremilast

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

Family Health History in Diverse Care Settings (FHH)

Improving Quality by Maintaining Accurate Problems in the EHR

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

Other Conditions in Detroit