Heart Disease Clinical Trials in Cleveland

Showing 361-380 of 521 trials

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial

NCT00583297

The ABCD clinical study (ClinicalTrials.gov Identifier NCT00187291) was designed to determine if a T-Wave Alternans (TWA) test is equivalent to an Electrophysiology Study (EPS) in predicting life-threatening heart rhythms in patients with ischemic heart disease, left ventricular dysfunction, and non-sustained tachycardia. The purpose of the ABCD Genetic sub-study is to identify genetic markers that predict TWA status and arrhythmia risk in this same population.

Ventricular TachycardiaCardiovascular DiseasesArrythmia+1 more

CardioDx400 participantsStarted Jan 2007

Cleveland, Ohio, United States

COMPLETEDPhase 3< 1 mile

Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)

NCT00088179

During a heart bypass procedure, a substance called "complement" is activated by the body. This "complement activation" causes an inflammatory response that can lead to side affects such as chest pain, heart attacks, stroke, heart failure, or death. The purpose of this study is to find out if the study drug (pexelizumab), that blocks "complement activation," can reduce such side effects and be given safely to patients requiring the bypass procedure with the use of the heart-lung machine.

Coronary Artery Disease

Alexion Pharmaceuticals, Inc.4,000 participantsStarted Jul 2004

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Birmingham, Alabama, United States +185 more locations

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial

Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)

Heart Disease Trials in Other Cities

Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)

Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure

Preliminary Assessment of Added Diagnostic Value of Dual Energy CT Images Using Data Acquired on a Spectral Detector CT

Naltrexone/Bupropion Cardiovascular Outcomes Study

The BOSS Study: An Acute Evaluation of Anatomical and Geometric Changes Using the Bladder on a Stick System (BOSS)

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

An Observational Study of Cholesterol in Coronary Arteries

AngioDefender Versus Brachial Artery Ultrasound Imaging

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

Geriatric Out of Hospital Randomized Meal Trial in Heart Failure

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

Extension Phase of the Chronicle® Offers Management to Patients With Advanced Signs & Symptoms of Heart Failure Study

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

A Prospective, Multi-Center, Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter in Facilitating Crossing Chronic Total Occlusion (CTO) Coronary Lesions

Combination Therapy Compared With Single-Drug Therapy in Patients With Cardiac Diseases

Educational Program for Various Health Literacy Levels to Improve the Health of Individuals With Heart Failure

Other Conditions in Cleveland