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Clareo Health | Epilepsy Clinical Trials in Philadelphia | 134 Studies

Clinical Trials EpilepsyPhiladelphia

Epilepsy Clinical Trials in Philadelphia

Find 134 clinical trials for epilepsy near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Epilepsy trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 81-100 of 134 trials

CompletedStudy Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) SeizuresThis study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine) extended-release with placebo in the treatment of Primary Generalized Tonic-Clonic…NCT00104416·Anniston, Alabama and 145 others

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Data from ClinicalTrials.govTerms

Enrolling by invitationClinical Trial of Vormatrigine in Adult Patients With EpilepsyOpen Label Extension Clinical Trial of Vormatrigine in Adult Patients with EpilepsyNCT07287163·Miami, Florida and 35 others

RecruitingRENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset SeizuresThis is a Phase 2 double-blind, randomized, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy, safety, and tolerability of SPN-817 in adults with…NCT06798896·Phoenix, Arizona and 62 others

CompletedPhase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label ExtensionThe study will evaluate the effectiveness and safety of an investigational drug-ganaxolone - on partial seizure frequency in adults with epilepsy taking a maximum of 3…NCT01963208·Birmingham, Alabama and 70 others

CompletedSafety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic DrugsThis is an 18-week, double-blind, multicenter study with gradual conversion from previous antiepileptic therapy to eslicarbazepine acetate monotherapy in subjects with partial…NCT00866775·Birmingham, Alabama and 105 others

CompletedCannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure DisorderThis is a multicenter, open-label trial to assess the long-term safety and efficacy of Cannabidiol Oral Solution as adjunctive therapy for pediatric participants with…NCT02318602·San Francisco, California and 10 others

CompletedConversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial EpilepsyThis study is being conducted to determine the effectiveness of a lower monotherapy dose of lamotrigine than that currently approved.NCT00355082·Alabaster, Alabama and 102 others

CompletedTopiramate as Adjunctive Therapy in Infants 1-24 Months for the Control of Partial Onset SeizuresThe purpose of this study is to evaluate the tolerability, safety and efficacy of topiramate in infants with refractory partial onset seizures (POS).NCT00113815·Birmingham, Alabama and 93 others

CompletedA 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic SeizuresStudy A0081106 is a 12-month open-label study to evaluate the long term safety and tolerability of pregabalin as add-on therapy in pediatric subjects 1 month to 16 years of age…NCT01463306·Tucson, Arizona and 150 others

CompletedRetigabine (Adjunctive Therapy) Efficacy and Safety Study for Partial Onset Refractory Seizures in EpilepsyThis Phase 3 study is being conducted to evaluate the efficacy and safety of retigabine dosed at 1200 mg/day, in three equally divided doses, compared with placebo in patients…NCT00232596·Birmingham, Alabama and 53 others

WithdrawnENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal SeizuresThe ENACT trial is designed to evaluate the efficacy and safety of ENX-101 administered adjunctively to current therapy in reducing seizure frequency in patients diagnosed with…NCT05481905·Phoenix, Arizona and 37 others

Active not recruitingA Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.This is a Phase 3 Study to examine the efficacy and safety of ZX008 in children and adults with cyclin-dependent kinase like-5 (CDKL5) deficiency disorder (CDD).NCT05064878·Birmingham, Alabama and 45 others

CompletedKetogenic Diet for Refractory Status EpilepticusThis research is being done to observe the safety, tolerability, side effects, and effectiveness of the ketogenic diet in people with continuous seizures (status epilepticus)…NCT01796574·Phoenix, Arizona and 8 others

TerminatedXEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic EncephalopathyTo investigate the potential antiseizure effects of adjunctive XEN496 (ezogabine) compared with placebo in children with KCNQ2 Developmental and Epileptic Encephalopathy…NCT04639310·Orange, California and 19 others

TerminatedNatural History Study of Infants and Children With Developmental and Epileptic EncephalopathiesThis is a multicenter, prospective, 2-year observational study in infants and children with developmental and epileptic encephalopathies (DEEs).NCT04537832·Los Angeles, California and 15 others

CompletedRufinamide Given as Adjunctive Therapy in Participants With Refractory Partial SeizuresTo evaluate the effect of rufinamide on total partial seizure frequency in adolescent and adult participants (12 to 80 years, inclusive) with refractory partial onset seizures…NCT00334958·Mobile, Alabama and 76 others

CompletedA Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.To evaluate the safety and efficacy of levetiracetam used as adjunctive treatment in pediatric subjects age 1 month to less than 4 years with partial onset seizures.NCT00175890·Birmingham, Alabama and 85 others

CompletedRandomized Therapy In Status EpilepticusThis study evaluated the effectiveness and safety of an investigational product (IP), intravenous (IV) ganaxolone, to treat participants with status epilepticus (SE).NCT04391569·Birmingham, Alabama and 73 others

CompletedRepeat Dose Safety Study of NRL-1 in Epilepsy SubjectsThis is a 12 month safety study to evaluate the safety of repeated doses of NRL-1NCT02721069·Little Rock, Arkansas and 4 others

CompletedRNS® System Pivotal StudyThe RNS® System Pivotal study is designed to assess safety and demonstrate that the RNS® System is effective as an adjunctive (add-on) therapy in reducing the frequency of…NCT00264810·Birmingham, Alabama and 31 others

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