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Clareo Health | Epilepsy Clinical Trials in Philadelphia | 134 Studies

Clinical Trials EpilepsyPhiladelphia

Epilepsy Clinical Trials in Philadelphia

Find 134 clinical trials for epilepsy near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Epilepsy trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 134 trials

TerminatedEfficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial SeizuresThis study will determine the safety and efficacy of pregabalin (Lyrica) when administered by itself (without any other anti-epileptic medication) to epilepsy subjects for the…NCT00524030·Northport, Alabama and 72 others

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Data from ClinicalTrials.govTerms

TerminatedStudy of EQU-001 for Uncontrolled Focal Onset SeizuresThis study is a Phase 2 multinational, double-blind, placebo-controlled, randomized (1:1:1), efficacy and safety study of adjunctive EQU-001 for the treatment of focal onset…NCT05473442·Boise, Idaho and 12 others

CompletedA 19-week Cognition Study of Levetiracetam in Children With Partial Onset SeizuresA 12-week Evaluation Period will be used to characterize potential cognitive and neuropsychological effects of LEV (20 - 60 mg/kg/day), as adjunctive treatment in children 4 - 16…NCT00105040·Birmingham, Alabama and 44 others

Enrolling by invitationAn Open-label Study of XEN1101 in EpilepsyThis study will evaluate the long term safety, tolerability, pharmacokinetics (PK), and efficacy of XEN1101 in subjects with Focal Onset Seizures (FOS) or Primary Generalized…NCT05718817·Phoenix, Arizona and 152 others

CompletedLevetiracetam: The Anti-Convulsant of Choice for Elderly Patients With DementiaElderly persons with dementia are at risk for seizures, however, traditional anticonvulsants are poorly tolerated in this population.NCT01318408·Philadelphia, Pennsylvania

RecruitingA Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic SeizuresThis is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of XEN1101 administered as…NCT05667142·Mobile, Alabama and 140 others

CompletedA Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial SeizuresThe purpose of this study was to evaluate the safety and pharmacokinetics of LCM syrup in children ages from 1 month to 17 years with uncontrolled partial seizures when added to 1…NCT00938431·Sacramento, California and 20 others

CompletedEfficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.To evaluate the efficacy and safety of diazepam in the management of refractory epilepsy in selected patients who require intermittent medical intervention for the control of…NCT00319501·Northport, Alabama and 85 others

TerminatedStudy to Evaluate the Long-term Safety and Tolerability of USL261 in Patients With Seizure ClustersThe purpose of this study is to examine the long-term safety and tolerability of USL261 in the treatment of seizure clusters.NCT01529034·Phoenix, Arizona and 57 others

CompletedEvaluation of the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial SeizuresThe purpose of this study was to evaluate the safety and tolerability of perampanel (up to 12 mg/day) given as adjunctive treatment in subjects with refractory partial seizures…NCT00735397·Birmingham, Alabama and 238 others

CompletedStudy to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant EpilepsyThe purpose of the study is to characterize the dose-response relationship with respect to efficacy of Padsevonil administered concomitantly with up to 3 anti-epileptic drugs…NCT03373383·Chandler, Arizona and 147 others

TerminatedStudy to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant EpilepsyThe purpose of the study is to evaluate the long-term safety and tolerability of Padsevonil administered at individualized doses as adjunctive treatment for subjects with…NCT03370120·Chandler, Arizona and 155 others

CompletedSafety and Tolerability Study of Diazepam Buccal Film (DBF) in Subjects With EpilepsyThis Phase 3, multicenter, open-label study of chronic, intermittent use of study drug (DBF) is designed to evaluate the safety and tolerability of the buccal formulation of…NCT03428360·Honolulu, Hawaii and 5 others

CompletedStudy Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal EpilepsyThis is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy.NCT06377930·New Haven, Connecticut and 11 others

Not yet recruitingCOMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"The goal of this clinical trial is to find out whether two existing medications-anakinra and tocilizumab-can effectively treat a rare and life-threatening brain condition called…NCT07281027·Phoenix, Arizona and 32 others

CompletedEquivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Chronic-Dose 4-Period Replicate DesignThe United States Food and Drug Administration (FDA) has specific rules generic drug companies must follow to get a generic copy of a seizure medication approved.NCT01713777·Birmingham, Alabama and 7 others

CompletedRNS System NAUTILUS StudyTo demonstrate that the RNS System for thalamic stimulation is safe and effective as an adjunctive therapy for the reduction of primary generalized seizures in individuals 12…NCT05147571·Birmingham, Alabama and 22 others

CompletedTrial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset SeizuresThe objective of this historical-controlled trial is to demonstrate the efficacy and safety of conversion to Lacosamide monotherapy in subjects with Partial-onset Seizures who are…NCT00520741·Alabaster, Alabama and 157 others

CompletedEvaluation of Efficacy and Safety of OXC XR as Adjunctive Therapy for Partial SeizuresEvaluation of the safety and efficacy of Oxcarbazepine XR as adjunctive treatment for adults with partial onset seizuresNCT00772603·Huntsville, Alabama and 70 others

CompletedStudy to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset SeizuresThe purpose of this study is to allow eligible subjects from the parent study, SP925 \[NCT00655551\] to continue lacosamide and to obtain additional long-term safety dataNCT00655486·Phoenix, Arizona and 6 others

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