Epilepsy Clinical Trials in Chicago

Showing 21-40 of 66 trials

Does Pregabalin Improve Symptoms of Anxiety in Patients With Epilepsy? A Comparison With Sertraline

NCT01309074

The aim of the study is to compare the safety \& efficacy of sertraline (up to a dose of 200mg/day) \& pregabalin (up to a dose of 300mg/day) for the treatment of symptoms of anxiety in patients with epilepsy.

EpilepsyAnxiety

Rush University Medical CenterStarted Nov 2009

Chicago, Illinois, United States

COMPLETEDNA2.2 miles

Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study

NCT03446664

Evaluate the initial safety and effectiveness of Microburst VNS stimulation in subjects with refractory epilepsy.

Epilepsies, PartialEpilepsy, Tonic-Clonic

LivaNova33 participantsStarted Feb 2018

Birmingham, Alabama, United States • Denver, Colorado, United States • Jacksonville, Florida, United States +6 more locations

COMPLETEDPHASE22.2 miles

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

NCT03283371

The primary efficacy objective of the study is to determine if adjunctive therapy of natalizumab 300 mg intravenous (IV) every 4 weeks reduces the frequency of seizures in adult participants with drug-resistant focal epilepsy. The secondary efficacy objective is to assess the effects of natalizumab versus placebo in drug-resistant focal epilepsy on additional measures of seizure frequency.

Epilepsy, Focal Seizures, Partial Seizures

Biogen67 participantsStarted Mar 2018

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +28 more locations

Does Pregabalin Improve Symptoms of Anxiety in Patients With Epilepsy? A Comparison With Sertraline

Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

Epilepsy Trials in Other Cities

Brivaracetam Safety and Efficacy Follow-up Study in Subjects With Epilepsy

Rufinamide Given as Adjunctive Therapy in Participants With Refractory Partial Seizures

Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure Pattern

Pharmacokinetics of Anti-epileptic Drugs in Obese Children

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus

A Study to Evaluate the Pharmacodynamic Activity of E2082 in Adult Participants With Photosensitive Epilepsy

A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601

Human Epilepsy Project 2: Resistant Focal Seizures Study

MR-Guided Focused Ultrasound in the Treatment of Focal Epilepsy (EP001)

Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

Neuroimaging Biomarker for Seizures

Staccato Alprazolam and Photoparoxysmal Response

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.

A Study to Look at the Efficacy and Safety of Keppra® Extended Release Formulation - XR

Other Conditions in Chicago