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Browse 7,874 clinical trials for diabetes. Find studies that match your criteria and connect with research centers.
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NCT05008276
Early diabetic kidney disease (DKD) occurs in 50-70% of youth with type 2 diabetes (T2D) and confers high lifetime risk of dialysis and premature death. Youth-onset T2D typically manifests during or shortly after puberty in adolescents with obesity. Epidemiological data implicate puberty as an accelerator of kidney disease in youth with obesity and diabetes and the investigators posit that the link between puberty and T2D-onset may explain the high burden of DKD in youth-onset T2D. A better understanding of the impact of puberty on kidney health is needed to promote preservation of native kidney function, especially in youth with T2D.
NCT05894252
The research will be conducted as a quantitative experimental study (as an intervention). For the primary DV, quality of life, there are two effective measures. * Health-related Quality of Life (HRQoL) scales of the SF-36 short form * Euro-QoL instruments (EQ-5D). Additionally, secondary variables assessed will be: * (Physical Activity (the International PA questionnaire, short form - IPAQ) * General Anxiety (the Generalised Anxiety Disorder Assessment - GAD-7 * Symptoms of Depression (the Patient Health Questionnaire - PHQ-9) * Habitual diet will be assessed with the EPIC food frequency questionnaire, * Memory function through the Gorilla online questionnaire (Memory Intrusion - TB1 and TB2). * Health locus of control (Multidimensional Health Locus of Control form C) Participants in the intervention group will be required to complete a 30-minute walk five days a week for 12 weeks. This will be in addition to any regular walking or exercise they are currently doing, which will be assessed via questionnaire at baseline. In the control group, participants will be asked to continue with their daily routines and usual level of physical activity. The baseline measurements will be taken before the intervention at week zero. Subsequently, all the participants will attend a virtual meeting (screening visit) to learn about the key aspects of the research, including the required actions of the control and intervention groups, how to use the act watch and report the required data. All participants in the intervention group and the control group will be required to wear acti-watches, which will be given to them for free. Participants in both groups will be asked to report the number of steps covered each week. Participants will report this information through an online link provided by the researcher. Each participant will access their data through an app that comes with the watch, however, the researchers will not have access to the app